STUDY OF GENE LINK TO DEPRESSION PROVIDES EVIDENCE OF BRAIN PROCESS

Exciting news from a research study, conducted by the University of Wisconsin-Madison, King's College London and the University of Otago in New Zealand has found that variations in the serotonin transporter gene (5-HTT) regulate chemical messengers in the brain.

Charleston, SC (PRWEB) July 20, 2003 -- Exciting news from a research study, conducted by the University of Wisconsin-Madison, King's College London and the University of Otago in New Zealand has found that variations in the serotonin transporter gene (5-HTT) regulate chemical messengers in the brain.

The study, announced by Terrie Moffitt, professor of psychology at UW-Madison, lends confirmation to the technical, system description of synapse function at http://www.enticypress.com .

Speaking in the press release from the University of Wisconsin-Madison dated 17, July 2003, This gene regulates levels of serotonin, a neurotransmitter that sends signals between nerve cells in the brain. Variations in the 5-HTT gene, says Moffitt, have been shown to influence an animal's response to stress."

The University reported: The researchers found that the interaction between the gene and past experience affected a person's likelihood of developing depression."

In the paper, Facing Your Brain, Taking Control", author Lee Kent Hempfling reports, If you have taken medication over time that is conducive to needing more to feel the same effect (habit forming drug) then you have experienced the overwhelming and seemingly uncontrollable urges, movements and antsy feeling brought about by stopping a synapse effecting drug."

The drug has either raised synapse transmitters to match levels a timed orchestrated brain would have and when removed has thrown you into a nearly uncontrollable mood change or depression cycle or the drug has lowered synapse transmitters to match levels of a timed non-orchestrated brain would have and when removed has thrown you into nearly uncontrollable mood change or depression cycle the outcome is the same."

You need the synapse levels to be at the range the drugs gave you in order to feel balanced but your brain is not genetically built to make that happen and you have lived for years with the unbalanced wave amplitudes telling you reality is something else."

"The stress-sensitive genotype predicted who will get depression about as well as a bone mineral density test can predict who will get a fractured hip, says Moffitt, in the University release. But she cautions that before new therapies or diagnostic tests for depression can be developed, the results of the study must be replicated."

"If replication studies confirm that genotypes can predict in advance who is vulnerable to life stresses that bring on depression, she says, 'this new knowledge could advance efforts to develop a diagnostic test of vulnerability to depression."

While this is exciting news for brain research, the implications of misreading this finding to develop drug therapies for treatment of serotonin reduction at an early age, may result in a drug dependency condition that will form the lifes experiences of the subject at an artificially high level of synapse transmission, the withdrawal from which, could cause severe depression, suicidal thoughts and worse.

Just as the architecture, provided by gene instruction, provides a mechanism for synaptic transmission and is able to be identified by its reduction from 'normal, the same process takes place in the brains dynamic system as part of normal thinking," said Hempfling. Therapies that address the system contribution to synaptic strength may accomplish the same enhancement result, without the impending dependency, on external chemical stimulation."

Facing Your Brain -- Taking Control: Overcoming Depression, Withdrawal & Imbalance", is published by EnticyPress.

About The Study:

To begin to understand this pervasive mental illness, researchers led by Moffitt and Avshalom Caspi investigated the interaction between genes and stressful events to determine if such an interaction could predict the future onset of depression." The press release is available at: http://www.news.wisc.edu/releases/view.html?id=8766 .

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