Sixty-Four Graduate Medical Students Got Drunk In The Name of Science

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A patented Prickly Pear Cactus Fruit Extract has been proven to prevent hangover symptoms and provide improved cognitive function the morning following drinking.

Everyone knows a sure way to avoid a hangover is to abstain from drinking alcoholic beverages, or at least to drink without overindulging. So why has a noted alcohol research team conducted a double blind placebo-controlled study at a major university where 64 participating med students got intoxicated at barbeque parties? What was the study looking to find?

The answer to this question reveals some sobering insights into the many misconceptions related to alcohol hangovers. The reason for the clinical trial was to see if a new patented herbal extract could prevent hangover symptoms which cause serious economic, societal and health problems throughout the world.

Dr. Jeffrey Wiese, the physician who led the unique investigation at Tulane University, is a respected medical professor and researcher who has conducted extensive prior research on the subject of alcohol hangovers. As a result, he and his medical associates have uncovered convincing data that suggests that the world can benefit from a hangover prevention “pill.”

In spite of the fact that many people may consider a hangover just punishment for a night of overindulgence, research shows that hangovers do not discourage drinking as people believe. Hangovers actually may encourage more drinking, as with the “eye-opener,” “hair of the dog,” and the morning Bloody Mary, etc.

A report entitled, "The Alcohol Hangover," published in The Annals of Internal Medicine, June 6, 2000, compiled by Dr. Wiese and his associates, points out that $148 billion is lost in the workplace yearly in America alone due to low productivity and absenteeism due to hangovers (an average of $2,000 per working adult). The report also says that a study of college students revealed that, “25 percent of college students reported experiencing a hangover in the previous week and 29 percent reported losing school time for hangover recovery.” Even more important, the study shows that people with a hangover experience diminished cognitive abilities that “may pose a substantial threat to themselves and others, despite having a normal blood alcohol level.” The research also points out that, “depression and other psychological disorders are more common in patients with hangover. And, hangover may also be an independent risk factor for cardiac death in patients with cardiac risk factors or coronary artery disease.” In addition the report revealed that hangovers are more common in light-to-moderate drinkers (70 percent) than heavy drinkers.

Most people (who drink) do not set out to consume enough to get a hangover when they imbibe socially. But one drink can lead to another and it doesn’t take serious overindulgence to wind up with a serious hangover. So, when Perfect Equation Inc. introduced a natural herbal extract formula, called HPF Hangover Prevention Formula™, that users insist actually “prevents” a hangover, instead of attempting to “remedy” one, the stage was set. Dr. Wiese and his associates agreed to put the product’s patented herbal extract, derived from the skin of the fruit of the Prickly Pear cactus, to the test.

Dr. Wiese organized the clinical study and was the lead investigator at Tulane. The study took place over three weekends to enable the crossover aspect to occur. The study group, comprised of 64 students (55 completed both arms of the study), was invited to participate in the “parties” that were like most any other college barbeque, with the exception of strict clinical controls that included careful participant identification; accurate alcoholic drink metering, monitoring and recording; breath tests and mandatory limo service.

The morning following the participants’ period of intoxication, a test session took place to assess the hangover symptoms, cognitive function and visual-spatial impairment of the candidates that were administered a placebo and those that were administered Tex-OE™, the patented extract in HPF Hangover Prevention Formula™. A report on the clinical study has been peer-reviewed by the American Medical Association and published in their medical journal, The Archives of Internal Medicine, June 28, 2004.

More information on the patented extract, Tex-OE™ contained in HPF Hangover Prevention Formula™ and how it works to prevent hangover symptoms and provide improved cognitive function, can be found by contacting the manufacturer, Perfect Equation Inc., and by visiting their websites: and

The manufacturer, Perfect Equation Inc., emphatically emphasizes that the product does not prevent intoxication and urges anyone who chooses to drink to never drink and drive.

For more information, contact:

Perfect Equation, Inc.

Gerald J. Stefanko

(760) 599-6079 ext. 307

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Gerald Stefanko