(PRWEB) December 3, 2004
Appetite suppressant drugs such as Phentermine work on the brain and central nervous system to suppress appetite. These medications promote weight loss by decreasing appetite or increasing the feeling of being full. They work by increasing brain chemicals such as serotonin which affect mood and appetite.
Xenical works in your digestive system to block about one-third of the fat in the food you eat from being digested and absorbed into your body. It does this by attaching to certain enzymes in your digestive system. When taken with meals, Xenical attaches to these enzymes and blocks those from breaking down some of the fat you have eaten. The undigested fat cannot be absorbed and the body eliminates them as waste.
Xenical has shown to not have some of the same serious side effects as the appetite suppressants since it does not deal with the brain and your central nervous system in attacking weight gain. Currently, all prescription medications to treat obesity except Xenical are controlled substances. A controlled substance is a drug whose general availability is restricted. Controlled substances include narcotics, stimulants, depressants, hallucinogens, and cannabis.
On October 29, 2004 Roche announced that the FDA has approved labeling showing that weight loss with Xenical (orlistat) delayed the onset of type 2 diabetes in obese patients with impaired glucose tolerance (IGT or pre-diabetes).
Currently Meridia and Xenical are the only weight-loss medications approved for longer-term use in obese patients, although the safety and effectiveness of these drugs have not been established for use beyond one year. Recently Meridia has been in the news as Dr. David Graham, associate director for science and medicine at the FDA's Office of Drug Safety, warned about the safety of Meridia and several other drugs. Meridia manufacturer Abbott Laboratories stands behind its product.
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