Acomplia Report to Have New Rimonabant News on March 8th

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Acomplia Report to Cover Latest Rimonabant Trial Results at American College of Cardiology Meeting in Orlando

Acomplia Report ( editors will provide on-scene coverage of the latest news about the obesity drug Acomplia (rimonabant) when it is presented at the American College of Cardiology meeting in Orlando on March 8th.

The eagerly awaited two-year results of clincal trials of Acomplia in Europe will end a four-month dry spell during which there has been little news about development of Acomplia (rimonabant).

The presentation of the first two-year results from the RIO-Europe study will take place at a special session devoted to late-breaking clinical trial news, and will be posted within minutes on the Acomplia Report (

The update will be presented by Dr. Luc Van Gaal, professor of Diabetology, Metabolism and Clinical Nutrition at Belgium's University Hospital Antwerp, who has been the principal researcher on the RIO-Europe clinical trial.

A commentary on the update will then be presented by Dr. Julius M. Gardin, chief of cardiology at St. John Hospital & Medical Center in Detroit.

Full coverage of expected news conferences related to the Acomplia (rimonabant) trials will also be posted on the Rimonabant Report (

First-year results from the RIO-Europe study fueled excitement over the potential of this new type of obesity drug when they were presented last August at the European Society of Cardiology (ESC) 2004 Congress.

The enthusiasm over this drug then surged in November, when two-year findings from the RIO-North America trial showed that Acomplia helped obese and overweight people lose significantly more weight -- and keep the weight off -- than a placebo.

With Sanofi reported still planning to file for initial regulatory approvals to sell Acomplia in the second quarter of this year, obesity experts are eagerly awaiting two-year results from the RIO-Europe trial for two reasons:

  • To see if the RIO-Europe trial continues to support the highly encouraging two-year findings from the RIO-North America trial.
  • To see if the RIO-Europe trial supports Sanofi's contention that side-effects from prolonged use of Acomplia do not appear to be a major issue.

Sanofi officials also seem certain to be questioned at the Orlando meeting about long-term data from its STRATUS trials, in which Acomplia is being evaluated for use in helping smokers break the habit.

The Acomplia Report ( and the Rimonabant Report ( are both published by Medical Week (, which also publishes Obesity Week (


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Milton Benjamin
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