Covalys Announces CTI Project Targeting First Use of SNAP-tag in Living Mice

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Covalys announces a joint CTI-project with the Ecole Polytechnique Fédérale de Lausanne targeting the use of ‘SNAP-tag for selective labeling of fusion proteins in living mice’.

this project will show once more that the SNAP-tag technology is an important tool in leading research. The use of NIR labels in living animals combined with the specificity of the SNAP-tag opens new routes for live animal research.

Covalys (http://www.covalys.com) is pleased to announce the start of a CTI project targeting first use of SNAP-tag in living mice. The project is funded by the Swiss government and will, over two years, establish the use of NIR (near infrared) labels as substrates for the SNAP-tag in living mice. Academic partners in the project are two research groups from the Ecole Polytechnique Fédérale de Lausanne (Swiss Federal Institute of Technology at Lausanne), the group of Prof. Didier Trono (Head of the Laboratory of Virology and Genetics) and Prof. Kai Johnsson (Head of Chemical Biology and inventor of the SNAP-tag technology).

“This project provides a unique opportunity to demonstrate the high specificity and versatility of the SNAP-tag in a system as complex as the living mouse,” said Prof. Johnsson.

“The development of methods for the selective labeling of proteins and biological structures inside living animals has enormous potential for applications in functional proteomics, developmental biology, and cancer research,” adds Prof. Trono.

According to Andreas Brecht, CEO of Covalys, “this project will show once more that the SNAP-tag technology is an important tool in leading research. The use of NIR labels in living animals combined with the specificity of the SNAP-tag opens new routes for live animal research.”

About Covalys Biosciences AG: Covalys provides products that help researchers in academic institutions and pharmaceutical and biotech companies to improve the efficiency of research into proteins and their function. Its SNAP-tag technology is the first commercially available protein tag which covalently links itself to any chemical probe provided as a substrate. ACP-tag allows site-specific labeling of proteins on cell surfaces. Covalys’ technologies are exclusively licensed from the Swiss Federal Institute of Technology Lausanne (EPFL). Founded in June 2002, Covalys has headquarters in Witterswil, Switzerland. For more information, visit Covalys’ website: http://www.covalys.com

Trademarks: SNAP-tag is a registered trademark of Covalys Biosciences AG.

Media Contact:

Andreas Brecht, CEO

Covalys Biosciences AG

Phone +41 (0)61 725 20 50

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