Anti-Aging Medical Headlines of 2006 Lead to Major Biomedical Advancements in 2007

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2006 was a banner year filled with many significant biomedical advancements and research findings with implications for enhancing the quality, as well as expanding the length, of the human lifespan. At the premier gathering of more than 6,000 physicians, scientists, and health professionals, the A4M highlighted some of the most promising aspects of biomedical advancements.

Chicago, IL (PRWeb) December 29, 2006  2006 was a banner year filled with many significant biomedical advancements and research findings with implications for enhancing the quality, as well as expanding the length, of the human lifespan. Of note:

December 2006: Low levels of testosterone hastened the development of Alzheimer's-like disease in mice but testosterone replacement prevented that decline, reported a research team from the University of Southern California. The brains of mice with low testosterone had increased levels of the protein beta-amyloid (which is associated with the development of Alzheimer's disease) in the brain and showed signs of behavioral impairment. The mice that received the testosterone had reduced accumulation of beta-amyloid and less behavioral impairment. The findings suggest that testosterone-based hormone therapy may prove effective in preventing and treating Alzheimer's disease in aging men, say the study's authors.

November 2006: Resveratrol, found in the skin of red grapes and cranberries and available as an over-the-counter dietary supplement, was found to reduce the risk of death and improve physiology in lab animals. Whereas mice fed a diet high in calories and fat gained weight and developed fatty livers, inflammation in their heart muscle, a diabetes-like condition, and died at a young age, mice that ate extra calories and fat  but were also administered resveratrol developed none of these medical problems, and maintained a physiology comparable to lean mice. Resveratrol-fed mice also outperformed both lean and overfed mice on tests of physical performance, and their risk of death was reduced by 30%. That same month, a separate research team reported that mice given resveratrol were leaner and developed an enhanced aerobic capacity, consuming oxygen more efficiently and containing greater numbers of healthy mitochondria (the energy-producing powerhouses of cells).

September 2006: Asian-American women in Bergen County, New Jersey, have an average life expectancy of 91.1 years, the average found by Harvard University researchers anywhere in the country for any racial subgroup in a county with a large enough number of deaths to be considered statistically significant. Factors associated with extraordinary longevity (as in the Asian-American women in Bergen county) include: high median income; college education or better; occupations in management or professional settings; diet emphasizing fruits, vegetables, fish, and green tea; and a lifestyle including Eastern healing techniques. It is also likely that this sub-population's immediate access to advanced preventive medical technologies that are the basis of anti-aging medicine contributed to the ability to detect and treat diseases and dysfunctions at a very early stage.

April 2006: Researchers from Italy's Institute of Clinical Physiology found that a regimen including supplements of omega-3, vitamin E, and niacin confers protection against heart disease. In a clinical trial involving nearly 60 men and women and lasting four months, those who took the supplement combination experienced a marked increase in total antioxidant capacity of the blood. The study's authors suggest that a number of complementing mechanisms, including a lowering of inflammation coinciding with increasing antioxidant activity, were responsible for the beneficial results on lipid profiles and oxidative status. For 2007, we can expect scientists to elucidate additional synergistic activities of multi-compound supplements for the treatment of disorders and diseases of aging.

February 2006: A multi-Institute collaboration of the National Institutes of Health (NIH) reported that heart health risk factors and lifestyle choices, such as exercise, learning new things, and staying socially connected, are associated with maintaining brain health as we age. The study found a key direct correlation between hypertension and cognitive decline, and that more-active seniors experienced less extensive cognitive decline. The report suggests that healthier living can significantly reduce mental decline, and for the New Year we can look to such interventions to reduce healthcare costs associated with Alzheimer's and other diseases affecting cognition and memory.

The year's anti-aging advancements may be best summed up by a statement made earlier this year by Dr. Shripad Tuljapurkar of Stanford University (USA). He reported that "…"[W]e are on the brink of being able to extend human lifespan significantly, because we've got most of the technologies we need to do it." Dr. Tuljapurkar estimates that between 2010 and 2030, the modal, or most common, age of death will increase 20 years if anti-aging therapies come into widespread use. This projected increase consequently increases the modal age of death in industrialized countries from 80 years, to a remarkable 100 years of age.

Observes Ronald Klatz, M.D., D.O., President of the American Academy of Anti-Aging Medicine (A4M; "In the coming years, we can look forward to the Life Extension Dividend, which extrapolates continued robust gains in life expectancy assuming successful application of anti-aging biomedical and technological advancements that are proven in the laboratory setting to expand the lifespans in multi-species studies." For more information on superlongevity factors and their potential impact on the human lifespan, visit

Continuing, Dr. Klatz comments: "The A4M has, over the past fourteen years, established a worldwide leadership role in educating clinicians in life enhancing, life extending medical technologies. The A4M is a leading provider of postgraduate medical education, training more than 100,000 physicians and scientists. For 2007, we are proud to announce the A4M expands its mission to embrace regenerative medicine, a medical specialty that applies advanced biomedical technologies for the purposes of renewing body tissues with the goal of maintaining the human body in normal-to-peak function for a prolonged period of time. With stem cell therapeutics, scientists aim to beneficially alter the very basic cellular sources of dysfunctions, disorders, disabilities, and diseases. Via therapeutic cloning, scientists will develop ample sources of human cells, tissues, and organs for use in acute emergency care as well as the treatment of chronic, debilitating diseases. Genetic engineering and genomics are important advancements that permit the identification and alteration of genetics to ameliorate dysfunctions, disorders, disabilities, and diseases. And, with nanotechnology, we can deploy micro- and molecular-sized tools to manipulate human tissue biology for microsurgical repair on a gross level, as well as microscopic nano-biology for repair at the most basic cellular level. Indeed, when taken collectively, the advancements offered by anti-aging and regenerative medicine to improve the quality of, and/or extend the length of, the human lifespan, are the singlemost potent emerging biomedical technologies today."

Adds Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman: "The year of scientific breakthroughs culminated with the convening of the Winter 2006 Session of the 14th Annual International Congress on Anti-Aging Medicine and Regenerative Biomedical Technologies. At this premier gathering of more than 6,000 physicians, scientists, and health professionals, the A4M highlighted some of the most promising aspects of biomedical advancements that took place in 2006 and beneficially impacted human longevity. We look forward to co-sponsoring the 15th Annual International Congress on Anti-Aging Medicine and Regenerative Biomedical Technologies in 2007. The Spring 2007 Session convenes April 26 to 28, 2007, in Orlando, Florida USA." For program details and Early Bird (Discounted) Registration, visit http://www.worldhealth,net/event.

Source: The American Academy of Anti-Aging Medicine (A4M), Chicago, IL

Contact: Catherine Cebula

Phone: (877) 572-0608

FAX: (978) 742-9719



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