CME Outfitters Announces neuroscienceCME Journal Club: "Adherence and Early Predictors of Response: Tools for Individualizing Treatment in Schizophrenia"

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CME Outfitters announces an upcoming neuroscienceCME activity titled "Adherence and Early Predictors of Response: Tools for Individualizing Treatment in Schizophrenia." Offered as an on-demand webcast accompanied by three live question and answer sessions, the activity will provide mental healthcare practitioners with the most recent data and clinical implications related to optimizing maintenance therapy in schizophrenia. The on-demand webcast and first live Q&A session will premiere on Monday, October 6, 2008.

CME Outfitters, LLC, an independent accredited provider of multidisciplinary medical education programming and related healthcare communications services, is pleased to announce an upcoming neuroscienceCME Journal Club series titled "Adherence and Early Predictors of Response: Tools for Individualizing Treatment in Schizophrenia."

Premiering Monday, October 6, 2008, the latest installment of neuroscienceCME Journal Club is a special series on schizophrenia. Alan I. Green, MD, Chair of the Department of Psychiatry at Dartmouth Medical School, will host three interviews on this topic. In each session, guest faculty will join Dr. Green to provide a brief synopsis of a recently published scientific work. Dr. Green and his guest will engage in a lively discussion about the merits of the article, its implications for the field of psychiatry, and key practice points arising from the data published in the article.

This educational activity will be made available as an on-demand webcast accompanied by three live question and answer sessions. CE credit is being offered for participation in the on-demand webcast.

There is no fee to participate or receive CE credit for this activity; however, registration is required. Three forms of registration are accepted:
Online: Visit the activity details page at and click the Register for Webcast icon. Links to register for each individual live Q&A session are also provided.
Phone: Call 877.CME.PROS (877.263.7767).
Fax: Visit the activity details page at, print and complete the activity details form, and fax to 240.243.1033.

Guest Host:
Alan I. Green, MD
Chair, Department of Psychiatry
Dartmouth Medical School
Lebanon, NH

Philip D. Harvey, PhD
Professor of Psychiatry and Behavioral Sciences
Emory University School of Medicine
Atlanta, GA

John M. Kane, MD
Chairman, Department of Psychiatry
The Zucker Hillside Hospital
Professor of Psychiatry, Neurology and Neuroscience
Albert Einstein College of Medicine
Glen Oaks, NY

Stephen R. Marder, MD
Director of VISN 22 Mental Illness Research Education Clinical Center
Dept. of Veterans Affairs
Director of the Section on Psychosis
Semel Institute at UCLA
Los Angeles, CA

Live Q&A Dates and Featured Articles:
October 6, 2008, 12:00-12:45 p.m. ET (Stephen R. Marder, MD/Alan I. Green, MD)
Kahn RS, Fleischhacker WW, Boter H, et al. Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial. Lancet. 2008;371:1085-1097.

October 27, 2008, 12:00-12:45 p.m. ET (Philip D. Harvey, PhD/Alan I. Green, MD)
Velligan DI, Diamond PM, Mintz J, et al. The use of individually tailored environmental supports to improve medication adherence and outcomes in schizophrenia. Schizophr Bull. 2008;34:483-493.

November 24, 2008, 12:00-12:45 p.m. ET (John M. Kane, MD/Alan I. Green, MD)
Leucht S, Busch R, Kissling W, Kane JM. Early prediction of antipsychotic nonresponse among patients with schizophrenia. J Clin Psychiatry. 2007;68:352-360.

Statement of Need:
Developing and following an effective maintenance treatment plan is vital to achieving remission and long-term functional recovery in patients with schizophrenia. Critical to selecting optimal pharmacotherapy in support of long-term recovery is appropriate weighing of the benefits, risks, and complexity of the treatment regimen. Each of these elements can impact adherence to pharmacotherapy, which in turn can impact outcome. Rates of medication nonadherence in patients with schizophrenia range from 40-55%. Recent evidence suggests that disease- and patient-related characteristics can predict the extent of adherence and can be used to tailor behavioral interventions. New data also indicate that early response to antipsychotic medications can predict longer-term outcome, and may allow physicians to abandon ineffective medications earlier in favor or more appropriate options. In this neuroscienceCME Journal Club series, experts will review cutting-edge data related to efficacy and safety of atypical antipsychotics, approaches to improving medication adherence, and strategies for identifying early non-responders, all of which will impact long-term functional outcome in patients with schizophrenia.

Learning Objectives:
At the end of this CE activity, participants should be able to:

  • Discuss the implications of differential efficacy and tolerability of antipsychotics on medication adherence.
  • Identify targeted behavioral approaches to improving treatment adherence in patients with schizophrenia.
  • Describe early predictors of response to antipsychotic medication in patients with schizophrenia.

Target Audience:
Physicians, physician assistants, nurse practitioners, nurses, psychologists, social workers, certified case managers, pharmacists, and other healthcare professionals interested in methods for optimizing outcomes with maintenance antipsychotic therapy in patients with schizophrenia.

Commercial Support:
CME Outfitters, LLC, gratefully acknowledges an educational grant from AstraZeneca Pharmaceuticals in support of this CE activity.

Credit Information:
The on-demand webcast offers CE credit for:

  • Physicians (ACCME/AMA PRA Category 1)
  • Nurses (CNE)
  • Pharmacists (ACPE)
  • Psychologists (APA)
  • Social Workers (NASW)
  • Certified Case Managers (CCMC)

All other clinicians will either receive a CME Attendance Certificate or may choose any of the types of CE credit being offered.
Credit Expiration Date: Tuesday, October 6, 2009

To receive CE credit for this activity, participants must view all three interviews in the on-demand webcast. Participation in the bonus Q&A sessions does not constitute additional credit or Live ACPE credit.

Post-tests, credit request forms, and activity evaluations can be completed online at (click on the Testing/Certification link under the Resources tab - requires free account activation), and participants can print their certificate or statement of credit immediately (70% pass rate required).

About CME Outfitters:
CME Outfitters develops and distributes live, recorded, print, and web-based educational activities to thousands of clinicians each year and offers expert accreditation services for non-accredited organizations. For a complete catalog of certified activities, please visit,, or call 877.CME.PROS (877.263.7767).

About neuroscienceCME: is the award-winning web portal serving clinicians, educators, and researchers in the neurosciences. Launched in October 2006, was custom designed to fill an identified gap in online resources for professionals around the world who are practicing in areas related to psychiatry, sleep disorders, addiction and substance abuse, ADHD, and other areas related to brain function. The site's primary mission is to be the professional's central forum for accessing, debating, synthesizing, and implementing the latest findings and best practices in the neurosciences.

About neuroscienceCME Journal Club:
neuroscienceCME Journal Club was designed for clinicians who have made a commitment to staying current. Each month, neuroscienceCME Journal Club will evaluate recently published literature and present it in a concise 45-minute audioconference+webcast format full of valuable takeaway points that can be immediately applied to clinical practice. To enhance their value as enduring clinical resources, all neuroscienceCME Journal Club segments are archived in their respective Clinical Knowledge Centers at The archives are updated frequently and indexed by date, topic, and guest author. Recorded Journal Club episodes are also offered as podcasts.

To view all recent neuroscienceCME press releases, visit and click on "News Room" or visit and search for "neuroscienceCME."

Clinical Compass, a bi-weekly e-newsletter published by CME Outfitters, is a convenient way to stay informed of all neuroscienceCME news and information. To subscribe, visit and click on "Subscribe to Clinical Compass."

Contact: Jessica Primanzon
CME Outfitters, LLC
240.243.1308 direct
240.243.1033 fax

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Jessica Primanzon