HolGenTech Demonstrates first-ever PDA Combination with High Performance Genome Computing at Boston Consumer Genetics Conference

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A stunned audience embraced the Genome Based Economy when HolGenTech Founder Dr. Andras Pellionisz debuted the first-ever consumer application for genome computing architected with High Performance hybrid GenomePC combined with a Personal Digital Assistant at the Consumer Genetics Conference in Boston on June 10. Affecting individual choices and creating new awareness and understanding of how the world around us impacts the one within us, the personal genome used by PDA presented a new vision of customers tooling up for the future imposed on us by breakthrough genomics and computing.

PDA Recommended Consumer Activity in the Genome Based Economy

the scientific community had to re-think long-held fundamentals.

The Google Phone demonstration introduced the imminent reality of the Genome Based Economy, as presented by HolGenTech Founder Dr. Andras Pellionisz at the Consumer Genetics in Boston the morning of June 10. HolGenTech Founder Dr. Andras Pellionisz demonstrated use of PDA for customers at the Consumer Genetics Conference in Boston in in the morning of June 10. Within hours, Illumina's CEO Jay Flately featured a different business model application for personal genomes in the Apple iPhone. The demonstrations of hand held device applications intended for personal genomes stunned the audience of approximately 400 with a view into how practical applications of our personal genomes will change everything. Dr. Pellionisz illuminated the potential of the personal genome when applied to shopping in the Genome Based Economy.

Using the Google Phone's built-in bar code reader, Dr. Pellionisz demonstrated how personal genome computing can detect genome-friendly and genome-supportive products from foods to cosmetics to building materials and beyond. In a demonstration, the PDA user was assumed to have a genomic proclivity to Parkinson's Disease. The demonstration leveraged the Google Phone's bar code reader to capture product information and a product rating scale to identify the prevention efficacy of any product under consideration. The consumer is equipped to make immediate product comparisons based on both personal health-preferences and genomic information with special consideration of the disease or syndrome of concern.

The HolGenTech Google Phone demonstration illustrated practical application of the personal genome, emphasizing how Personal Genome Analysis can be used as a tool for an individual to pursue Personalized Consumer Activity based on one's DNA. The demonstration elucidated how disease prevention--or health--hinges on optimizing epigenomic pathways through foods, food additives, vitamins, cosmetics, chemicals, and environments to best fit or fix one's genome. In a completely different and contrasting model, Illumina's iPhone demonstration focused on reading one's genome information for the purpose of comparison to others'.

The Personal Genome Computer -- a tool for the Genome Based Economy

"The Personal Genome Computer is the catalyst tool for the Genome Based Economy. We look to chip-makers, Intel, AMD, Xilinx, and Altera, and to integrators like HP, Dell, DRC, and even IT giants like Google and Microsoft for next developments in parallel processing to produce HPC desktop- and server-lines as the IT infrastructure of the Genome Based Economy," said Dr. Andras Pellionisz. "As high performance computing, custom algorithms and post-ENCODE genomics align, more personalized medicine and health care, wellness, prevention, and DNA-informed personal and lifestyle choices are realized. With affordable access to and utility of our personalized genome we can experience personalized everything from health care to food to clothing to housing and environmental choices, even to friends....everything suited to one's personal genome."

In the HolGenTech presentation in Boston, Pellionisz outlined the unprecedented computing-challenge posed by the oncoming avalanche of affordable full genome sequences which require in-depth analysis to be useful. Today "Direct-to-Customers" genome testing companies, such as DeCodeMe, 23andME, and Navigenics, rely on Illumina/Affymetrix microarray-technology to interrogate up to 1.6 million SNP-s (single nucleotide polymorphisms, point mutations of the 6.2 billion A,C,T,G letters/amino acid bases of human DNA), though the field of genomics is already beyond SNP-s and awaits the next developments in nano-sequencing technology, which promise affordable and readily available personal genomes by the second half of 2009.

Landmark Principles in Action

The Consumer Genetics Conference coincides with the second anniversary of the epoch-making release of ENCODE results, when mastermind Frances Collins, the most prominent keynote speaker at the conference, declared, "the scientific community had to re-think long-held fundamentals." In response to Francis Collins' direct call, Dr. Pellionisz published The Principle of Recursive Genome Function. Emerging from the conference, a new consensus demands advanced computational mechanisms to search for much more complex (mal)formations of full DNA sequences. While the new Illumina microarray extends utility up to 4 million points and includes the ability to spot over 10 thousand "copy number variations," Pellionisz' research points to the problem of algorithmic, recursive genome regulation, where genome regulation derailments require intricate searches for cancer-stopping microRNA-s, silent mutations, repeat motifs and fractal defects.

About HolGenTech:
HolGenTech leads the way in accelerating genome computing analysis with software addressing the applications for a Genome Based Economy. The Silicon Valley based company was founded on the basis of HoloGenomics: the synthesis of Genomics and Epigenomics expressed in Informatics. The company is currently engaged in securing Series A or micro-funding for a rapid ignition to develop the personal genome based consumer shopping model.


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Suzanne Matick: PR, Investor Relations
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