50 Millionth Unique Chemical Substance Recorded in CAS REGISTRY

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On September 7, Chemical Abstracts Service (CAS) recorded the 50 millionth substance in CAS REGISTRY, the world's most comprehensive and high-quality compendium of publicly disclosed chemical information. The registration marks a significant milestone not only for CAS, but for the scientific community as a whole. The scientific knowledge amassed and chronicled in REGISTRY by CAS scientists enables continued discovery by chemists and researchers around the globe.

Few therapeutics are approved by the US Food and Drug Administration and other regulatory agencies for the treatment of neuropathic pain.

Chemical Abstracts Service (CAS), a division of the American Chemical Society, announced that on September 7 it recorded the 50 millionth substance in CAS REGISTRY, the world's most comprehensive and high-quality compendium of publicly disclosed chemical information. The recently registered substance is a novel arylmethylidene heterocycle with analgesic properties. Reaching the 50 million mark so quickly is an indicator of the accelerating pace of scientific knowledge. CAS registered the 40 millionth substance just nine months ago--in contrast, it took 33 years for CAS to register the 10 millionth compound in 1990.

Key Facts:

  • CAS REGISTRY is the most comprehensive collection of disclosed chemical substance information in the world. It contains 50 million unique organic and inorganic substances, such as alloys, coordination compounds, minerals, mixtures, polymers and salts, and more than 61 million sequences.
  • CAS registered its 40 millionth substance just nine months ago--in contrast, it took 33 years for CAS to register the 10 millionth compound in 1990. The predominant source of new chemical substance information being entered into REGISTRY is global patent literature.
  • More than 1,500 universities, top fortune 500 corporations, and all major patent offices use CAS' products to access the CAS REGISTRY for the comprehensive, current, reliable data they need to enable scientific discovery.
  • The 50 millionth substance (CAS Registry Number® 1181081-51-5) was registered by CAS scientists from the Examples section of a nearly 200-page patent issued by the World Intellectual Property Organization. According to the patent, "Few therapeutics are approved by the US Food and Drug Administration and other regulatory agencies for the treatment of neuropathic pain." To address this concern, a series of novel arylmethylidene heterocycles were synthesized, which included the most recent substance registered by CAS.

Quote attributable to Dr. Matthew Toussant, Senior Vice President Of Editorial Operations, CAS:
"The 50 million substances in CAS REGISTRY have the potential to enable new discoveries in every field of scientific study, from cancer research to the development of new consumer goods, the creation of more effective drugs, or the discovery of faster and smaller computer processors. Scientific discoveries build upon past discoveries, and it is the quality and comprehensiveness of CAS REGISTRY that enables chemistry innovation."

Quote attributable to Grace Baysinger, Head Librarian, Swain Chemistry and Chemical Engineering Library, Stanford University:
"CAS REGISTRY is an indispensable resource for users in research, education, and industry. The rapid growth of CAS REGISTRY is a mirror of the breadth and depth of creativity in research labs throughout the world."

About CAS REGISTRY
REGISTRY is the only integrated collection of chemical information from a full range of patent and journal literature, plus Web and other commercial sources that is curated and quality-controlled by a global team of scientists. REGISTRY not only provides chemical names, the unique CAS Registry Number, and vital literature references but also ancillary information such as experimental and predicted property data (boiling and melting points, etc.), commercial availability, preparation details, spectra, and regulatory information from international sources.

About CAS
CAS, a division of the American Chemical Society, provides the world's largest and most current collection of chemical and related scientific information, including the most authoritative database of chemical substances, the CAS REGISTRYSM. CAS combines these databases with advanced search and analysis technologies to deliver the most complete, cross-linked, and effective digital information environment for scientific research and discovery, including such products as SciFinder, STN, STN Express®, and STN® AnaVistTM, among others.

For more information, please visit - http://www.cas.org or http://www.delicious.com/caspresskit.

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Crystal Poole Bradley
CAS
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