Abstracts Online for New Horizons in Toxicity Prediction: The 2nd International Lhasa Symposium

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Presentation abstracts are now available online for Lhasa Limited’s 2nd International Symposium on New Horizons in Toxicity Prediction. The event is organised with support from media partner The Royal Society of Chemistry (RSC) and will be hosted at Leeds Royal Armouries Museum in the UK on 15th - 16th September 2010.

Presentation abstracts are now available online for Lhasa Limited’s 2nd International Symposium on New Horizons in Toxicity Prediction. The event is organised with support from media partner The Royal Society of Chemistry (RSC) and will be hosted at Leeds Royal Armouries Museum in the UK on 15th - 16th September 2010.

Day One Agenda Highlights:

The event will open with a plenary session presented by Dr Thomas Hartung, Director of the Center for Alternatives to Animal Testing (CAAT) and the Doerenkamp-Zbinden Professor and Chair for Evidence-based Toxicology in the Department of Environmental Health Sciences at the Johns Hopkins Bloomberg School of Public Health. Dr Hartung’s presentation will explore the differing US and European approaches to toxicity studies.

Day one will also feature presentations on good practices for building robust QSAR models, The Predictive Safety Testing Consortium and the OECD Toolbox. The Royal Society of Chemistry’s Antony Williams will present the ChemSpider online chemical database and Thomas Holmes of APC will share his experiences on the application and impact of the EU REACH legislation. The day will close with a session on metabolism mediated toxicity prediction which will be delivered by Dr Thomas Baillie of the University of Washington. Dr Baillie will discuss an integrated approach to toxicity testing in drug development, where the primary goal is to minimize the likelihood of toxicity due to chemically reactive metabolites.

A poster presentation session will coincide with a networking luncheon on day one, and the Symposium dinner will also take place on the evening of September 15th. This will include a drinks reception and three course meal stylishly hosted in Royal Armouries Hall. Further details can be found on the event website.

Day Two Agenda Highlights:

September 16th will begin with a plenary session from Dr Jim Bridges, head of the European Institute of Health and Medical Sciences. Dr Bridges will set the theme for the second day with a presentation on emerging areas in toxicity prediction.

Dr Eric Blomme of Abbott Laboratories will review how toxicogenomics can be used to predict and characterise the toxicological profile of compounds at an early product development stage with a particular emphasis on the strengths and limitations of technology. Using specific examples, he will illustrate how toxicogenomics can be successfully implemented in a discovery or preclinical organization.

Other presentations on day two will look at transporter modelling, metabolomics in toxicity assessment and systems biology. The afternoon session will feature a talk on TK/TD prediction and close with a session from Dr Chris Portier of the National Institute of Environmental health Sciences. Dr Portier will discuss the identification of susceptible subpopulations in the prediction of toxicological risks and the extent to which they may play a role as newer methods arise for evaluating health risks.

Registration and Details: http://www.lhasasymposium.com

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Lisa Wayman
Lhasa Limited
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