ATCC Introduces Primary Human Umbilical Vein Endothelial Cells for Cardiovascular Research

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ATCC (American Type Culture Collection), the world’s largest and most diverse bioresource center, offers human umbilical vein endothelial cells (HUVEC) as part of its Primary Cell Solutions for cardiovascular research.

ATCC (American Type Culture Collection), the world’s largest and most diverse bioresource center, offers human umbilical vein endothelial cells (HUVEC) as part of its Primary Cell Solutions for cardiovascular research. Characterized cell lines are supplied with optimized media, growth factors and reagents.

These primary cells are derived from either single donors or from a pooled population of unique donors. Pooled primary HUVECs minimize the lot-to-lot variation associated with single donor lots while yielding larger lot sizes – assuring greater consistency in large scale studies. Human umbilical vein endothelial cells are an ideal model system for studies involving angiogenesis, arteriosclerosis, oxidative stress, tubule formation, wound healing, immune response and drug screening.

ATCC® normal primary Human Umbilical Vein Endothelial Cells are cryopreserved in the first or second passage to ensure the highest viability and plating efficiency, and thoroughly tested for sample purity. Each lot of cells will grow for at least 15 population doublings while maintaining normal morphology and functionality.

HUVECs from ATCC are demonstrated to be positive for von Willebrand factor and negative for smooth muscle alpha-actin. They are performance tested together with media, growth supplements and reagents to guarantee reliability as part of ATCC® Primary Cell Solutions™, a system of matched components designed to maximize growth and functionality, and maintain normal morphology for specific cell types.

When HUVECs are grown in Vascular Cell Basal Medium, supplemented with their corresponding cell line-specific growth kits, an ideal culturing environment for propagation in low serum conditions (2% FBS or less) is created. Endothelial Growth Kit-VEGF contains several purified recombinant human (rh) growth factors (rh BEGF, rh EGF, rh FGF basic and rh IGF-1) combined with heparin and hydrocortisone to support a faster rate of proliferation. Endothelial Growth Kit-BBE contains bovine brain extract (BBE) and is specified when a less defined cell culture medium is desired. ATCC Primary Cell Solutions systems enable researchers to grow high quality cultures reliably and consistently — with expert support if needed.

To learn more go to http://www.atcc.org/PCS2. To speak with an expert or place an order, call toll free 1-800-638-6597 in the U.S. and Puerto Rico, or international callers can dial +1-703-365-2700.

ABOUT ATCC
ATCC maintains the largest and most diverse biorepository in the world. The innovative, not-for-profit organization develops and provides products for life science research, services to support biotechnology development, and standards that are consistent with its mission – to acquire, authenticate, preserve, develop, and distribute standard reference microorganisms, cell lines, and related materials for research in the life sciences. With distribution to more than 140 countries and a working relationship with 12 distribution partners, ATCC has the experience, knowledge, rigorous methodologies, standards, longevity and the global reach to serve academic institutions, government agencies, biotech, biopharma, and research organizations around the world.

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