New Articles About Chromatin, IVIG and Mukoviszidose Published at

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The Science Magazine publishes articles in all areas of biological science. The latest articles cover Chromatin which is is the combination of DNA and proteins that define the contents of a cell nucleus, IVIG which is a blood product containing the pooled IgG (immunoglobulin antibody G) extracted from blood plasma. The article on Mukoviszidose covers cystic fibrosis which is a genetic disease affecting the lungs, pancreas, liver and intestine.

The Science Magazine publishes articles in all areas of biological science including biology, agriculture, horticulture, forestry, geography, environment and health. Drawing from this pool of scientific disciplines, it publishes articles, reviews and insights on biological topics including those which have recently become popular. Most of these reviews are included in the EurekaMag BioScience Keyword Category and in the EurekaMag BioScience Reviews Category of the online science magazine.

The insight into Chromatin covers the combination of DNA and proteins that make up the contents of the nucleus of a cell. As such chromatin's functions include packaging DNA into a smaller volume to fit in the cell, strengthening the DNA to allow mitosis and meiosis and prevent DNA damage, and controlling gene expression and DNA replication. The article presents the results of experiments which indicate that at least part of the RNA synthesized by chromatin is competed for in hybridization by purified ribosomal RNA and that the interphase chromatin takes the form of coarse, dense strands which form a complex reticulum. It also discusses the function of chromatin during seed germination: scientists discovered a dramatic increase in chromatin-bound deoxyribonuclease activity in the embryonic axis immediately prior to the onset of DNA replication. Active growth processes coincided with the highest RNA polymerase activity, as well as the greatest template accessibility, during sprouting of potato. Consequently, chromatin-associated RNA and protein content was highest in young developing tubers and in old tubers at the onset of sprouting. Ribosomal RNA content, in turn, was highest in small tubers, remained constant during dormancy, and decreased when sprouting began, probably due to the translocation of rRNA into the sprouts. presents an insight into IVIG which is intravenous immunoglobulin containing the pooled IgG (immunoglobulin antibody G) extracted from the plasma of over one thousand blood donors. The insight into intravenous immunoglobulin (IVIG) covers IVIG treatment for various disorders. A favorable response to the treatment hinges on the prompt initiation of therapy in disorders such as in pneumonia, adenovirus infection, multiple sclerosis, and Guillain-Barre syndrome which is a serious disorder that occurs when the body's defense (immune) system mistakenly attacks part of the nervous system. IVIG is also an effective and safe treatment for anemia. Following initial treatment with an infusion of intravenous immunoglobulin there was a recurrence of severe anemia after three months after which retreatment with IVIG resulted in normalization of hemoglobin and a significantly longer remission duration.

The insight into Mukoviszidose covers the disease cystic fibrosis affecting most critically the lungs, and also the pancreas, liver, and intestine. Mukoviszidose is caused by a mutation in the gene for the protein cystic fibrosis transmembrane conductance regulator (CFTR). This gene is required to regulate the components of sweat, digestive juices, and mucus. Many calculated values useful as indices of essential fatty acid status indicated that essential fatty acid deficiency exists in cystic fibrosis. Treatment of cystic fibrosis patients with safflower oil, however, did not correct the aberrations in fatty acid pattern. In the plasma of cystic fibrosis patients, levels were elevated for copper, ceruloplasmin, total globins, and total proteins and were depressed for iron, vitamin D, vitamin A, carotene, and albumin. Other authors conclude that there is a wide range of duodenal pH values found in patients with cystic fibrosis and that the efficiency with which enzyme supplements work is closely related to these pH levels.

The Science Magazine was launched in November 1998 as the online version of the French science magazine "Eurêka - Le magazine des sciences" published since 1995. During the past decade, it has emerged as a comprehensive aggregator of information on biology, on the applied life sciences agriculture, horticulture and forestry, on the earth sciences, on the environmental sciences, and on the health sciences.

The Science Magazine has recently been accredited by the Chinese Ministry of Industry and Information Technology with the Internet Content Provider (ICP) Number 10204677. The site delivers its content through a number of RSS feeds including a "Most Shared Content" RSS Feed and an @EurekaMag Twitter account. The @EurekaMag Twitter account currently features 45,348 tweets and 828 followers. The site accepts advertisements through the Google AdWords system.


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