New Scientific Information on Cerebrum, DAPI and Isaac Newton Published

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The Life Sciences Website publishes articles in all areas of biological science. The latest articles cover Cerebrum which is a part of the forebrain directing the conscious or volitional motor functions of the body, DAPI which is a fluorescent stain that binds strongly to A-T rich regions in DNA and is extensively in fluorescence microscopy. The article on Isaac Newton covers one of the greatest and most influential physicist, mathematician, astronomer, natural philosopher, alchemist, and theologian of all times.

The Life Sciences Website publishes articles in all areas of the life sciences including biology, agriculture, horticulture, forestry, geography, environment and health. Drawing from this pool of scientific disciplines, it publishes articles, reviews and insights on biological topics including those which have recently attained attention. While the Life Sciences Research Category contains over 36 million references, most of the reviews are included in the Life Sciences Keyword Category, the Life Sciences Keyphrase Category and in the Life Sciences Reviews Category of the online science magazine. All content is now available on a user-friendly and fast Mobile Website.

The review of the cerebrum covers the largest and most highly developed part of the human brain. It encompasses about two-thirds of the brain mass and lies over and around most of the structures of the brain. The cerebrum is involved in several functions of the body including determining intelligence, determining personality, thinking, perceiving, producing and understanding language, interpretation of sensory impulses, motor function, planning and organization, and touch sensation. The review covers autopsy of dogs infected with Taenia multiceps and Echinococcus granulosus. Coenurus cysts could be found in a side ventricle, in the cerebellum or in the cerebrum. Another study reveals that multiple sclerosis signal changes and focal atrophy of the cerebrum, cerebellum, and corpus callosum in patients with incontinentia pigmenti and neurologic disorders. In a study discovering extracellular signals involved in tissue inhibitors of metalloproteinases (TIMP) production in the brain, Ala-ET-1 which is an ETB receptor agonist, was administered and increased the level of TIMP-1 mRNA in rat hippocampus, caudate-putamen and cerebrum. Ala-ET-1 increased the level of TIMP-3 mRNA in the cerebrum, but not in the hippocampus or caudate-putamen. TIMP-2 mRNA was not affected in these brain regions whereas Ala-ET-1 also stimulated the production of TIMP-1 and TIMP-3 proteins in the cerebrum. presents a review on DAPI which is a fluorescent stain that binds strongly to A-T rich regions in DNA. DAPI is a popular nuclear counterstain for use in multicolor fluorescent techniques. Its blue fluorescence stands out in vivid contrast to green, yellow, or red fluorescent probes of other structures. When used according to our protocols, DAPI stains nuclei specifically, with little or no cytoplasmic labeling. The blue-fluorescent DAPI nucleic acid stain preferentially stains dsDNA; it appears to associate with AT clusters in the minor groove. Binding of DAPI to dsDNA produces a 20-fold fluorescence enhancement, apparently due to the displacement of water molecules from both DAPI and the minor groove. One study showed that staining of of Cryptomonas cells with DAPI, a DNA-specific fluorochrome used in conjunction with epifluorescence microscopy, permitted clear examination of both embryo and anomalous nuclei through the extremely transparent integuments of the seeds. The discrete DAPI fluorescence pattern of the triplet nuclei was used as the primary feature through which they were tentatively identified as failed constituents of triple fusion.

The review on Isaac Newton covers the classical laws quantified by the physicist, mathematician, astronomer, natural philosopher, alchemist, and theologian. According to quantum mechanics, particles leap from point to point, occupy several places simultaneously, and appear to communicate faster than the speed of light. Nevertheless, as Austrian physicist Erwin Schrodinger pointed out, everyday objects, although made of atoms, do not behave in this way but obey the predictable classical laws quantified by Isaac Newton. Scientists have now started to examine the boundary between the classical realms of Isaac Newton and quantum realms. By cooling particles with laser beams or by moving them through special cavities, they have produced individual electrons and atoms that reside in two places at the same time and electromagnetic fields that vibrate in two different ways at once. Another key aspect of this review is the history of color theory. Up to 1600 there was more work published in the field of visual theory than in that of color theory. Photobiologic studies of sunlight date back to Sir Isaac Newton in 1671. During the scientific revolution the nature of light has become the focus of attention. While Goethe needed more than 500 pages for the historical section of his Farbenlehre, it was not until the second half of the twentieth century that the connection between color vision and the physiology of the nervous system was made.

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