Veterans Affairs Study Suggests Injuries From Chronic Alcohol Ingestion Was Lower, When Participants Consumed Betaine, a Derivative of a Specific Nutrient

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Expanding on this newly published study, Nutri-Med Logic Corp states that the primary food source for Betain is Choline, a nutrient, which was declared essential. In 1998, the Food and Nutrition Board of the Institute of Medicine declared Choline a precursor to Betaine and established dietary reference intake for Choline. The main criterion for establishing intake reference for Choline was for maintaining liver health. While this study was done with liquid Betaine, but proper and adequate Choline supplementation would achieve the same outcome.

Nutri-Med Logic Corp: A New Study by Veterans Affairs Nebraska-Western Iowa Health Care System, Published in International Journal of Hepatology, suggests that when animals were fed alcohol with liquid betaine, there were lower indices of Fatty Liver.

The primary food source of betaine is choline, a nutrient found in vegetables and animal liver. In the human body, choline biologically converts to Betaine (tri-methyl Glycine) and studies going back to 1954 have established that alcohol consumption increases the requirement of choline intake. J Exp Med. 1954 Dec 1;100(6):615-27

Choline belongs to a group of nutrients known as Electrophilic Methyl Group (EMG), which have been suggested to eliminate a by-product of alcohol metabolism called NADH, responsible for accumulation of fat in the liver. NADH is a molecule that is normally associated with the production of energy (citric acid cycle) but it is also produced, in excessive amount, in the case of alcohol consumption and thus interferes with the normal metabolism of fat in the liver (Fatty Liver).

Methyl groups return NADH to its active status, that being NAD and, thus, offers some protective role in the case of alcohol and liver.

Choline, a methyl donor, was declared essential and a precursor to betaine by The US Institute of Medicine, who established a dietary reference intake for choline. On June 5, 2001, FDA offered National Academy of Sciences the opportunity to comment on the authoritative statement cited by the Food and Nutrition Board of the Institute of Medicine, relating to Dietary Reference Intakes for several nutrients including Choline. FDA received no comment from National Academy of Sciences. FDA reviewed the authoritative statement from Dietary Reference Intakes for Choline and has not acted to prohibit or modify the claim.

Thus, under the Provision of The FDA labeling guidelines, any supplement that would provide 55mg of choline is considered a “good source” of Choline.

In conclusion, Nutri-Med Logic Corp. agrees with this newly published study but adds that choline is the precursors to betaine and, further, since choline not only offers protective role for the liver but also in the cardiovascular system (transmethylation of homocysteine), precursor to acetylcholine, precursor to phospholipids (key component of immune system) future studies should promote the dietary intake of choline.

Nutri-Med Logic Corp, also, adds, while the best way to protect the liver from alcohol-induced injuries would be no alcohol, but for those who consume alcohol, choline supplementation would be very beneficial.

Nutri-Med Logic Corp is the producer of Poly-Enyl-phosphatidyl-choline (PPC 425mg), a natural lecithin extracted from soy and an efficient and pure source of choline.

PolyEnylPhosphatidylCholine has been the recommended dietary supplement of choice for those with Fatty Liver and Alcoholic Liver Disease, for about half century in Europe.

Nutri-Med Logic’s PPC 425mg was formulated to provide 55mg of Choline, a “Good Source” of Choline dietary supplement.

Nutri-Med Logic Corp. is also the producer of a Natural, Balanced, Deodorized and Concentrated Omega-3, which is also a Pharmaceutical Grade Omega-3.

Nutri-Med Logic's products ( are Formulated Based on Nutritional Logic, made from the highest quality raw materials that are manufactured in pharmaceutical facilities, encapsulated in pharmaceutical facilities and packaged in pharmaceutical facilities.

It must be noted that the studies, sources or statements above have not been evaluated by The FDA and, thus, one should not relate the cause or diagnosis of any diseases, stated herein, to lack of the dietary supplements stated herein; nor equate their supplementation to prevention, treatment or cure.


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H.R. Zadeh
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