NYU’s SOLVE Receives Multi-Million Dollar HIV Grant

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New York University School of Medicine’s Section on Value and Effectiveness (SOLVE) and Yale Schools of Medicine and Public Health have received a five-year grant for HIV and alcoholism research.

The Consortium to Improve Outcomes in HIV/AIDS, Alcohol, Aging, and Multi-Substance use (COMPAAAS), led by New York University’s Section on Value and Effectiveness (SOLVE) and Yale’s Schools of Medicine and Public Health, has been awarded a five-year $11,250,000 grant from the National Institute on Alcohol Abuse and Alcoholism.

COMPAAAS builds on 10 years of observational and pilot intervention work conducted within the Veterans Aging Cohort Study (VACS) of over 120,000 United States veterans, which includes 40,000 individuals living with HIV. In an effort to understand the effects of alcoholism on HIV transmission and determine what additional evidence is still needed, the group will expand current alcohol intervention studies using a stepped care approach. This grant will enable VACS to continue its research for a minimum of five more years.

Scott Braithwaite, M.D., associate professor of medicine at New York University, David Fiellin, M.D., professor of medicine, investigative medicine and public health at Yale School of Medicine, and Amy Justice, M.D., professor of medicine and public health at Yale, are the principal investigators of the intervention and operations research grants.

Dr. Braithwaite's project will use mathematical models to compare data from COMPAAAS observational and intervention work with other research evidence to determine the cost-effectiveness of a portfolio of potential health interventions. The results of these research projects will likely determine individualized care for those with HIV infection.

Dr. Braithwaite stated, “I am thrilled to receive this award. This grant will fund work that is an important part of reducing the number of new HIV infections in the United States.”

Fiellin's grant supports a multisite randomized trial focusing on decreasing health consequences of unhealthy alcohol use in HIV infected individuals using an integrated stepped care approach. The team measures alcohol consumption, alcohol injury and the progression of HIV.

Dr. Justice primarily examines the independent effects of alcohol use and abuse, aging, HIV infection, and HIV treatment, as well as the interaction between these factors.

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Brianna Ladapo
NYU Medicine
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