Nutri-Med Logic Corp Says that a Recent Study by the Dept. of Neurology, Univ. of Oregon Health & Science, Highlights the Benefits of Omega-3 Diet in Multiple Sclerosis

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Nutri-Med Logic Corp says that the conclusion of combined results from the in-vitro study and the open-label study in Multiple Sclerosis, points to the DHA and EPA, the two Omega-3 Polyunsaturated fatty Acids, as a vehicle to slow-down the migration of immune cells in the central nervous system / brain, responsible for the development and progression of MS.

Nutri-Med Logic Corp: A recent study done by the Department of Neurology, Oregon Health & Science University and the Department of Veterans Affairs Medical Center, Portland, OR, suggests that when brain cells were pre-treated with EPA and DHA, two Omega-3 polyunsaturated fatty acids, the migration of certain immune cells responsible for the destruction of nerves coating (myelin sheaths) were lowered.

According to the study, Multiple Sclerosis "MS" is an inflammatory disease, which causes certain immune cells to be over-reactive.

Inflammation is an immune mechanism. In a very primitive manner of speak, inflammation to the immune cells is like smoke to fire, a signal that there is a problem. The immune cells from far away can only be made aware of their need through inflammatory signals. Inflammation and inflammatory signals, as it would relate to the immune system, are interchangeable. An inflammatory disease is a condition when the inflammation does not subside.

In Multiple Sclerosis, due to the inflammatory signals, the immune cells (immune system) do not stop and thus they damage the tissue, including myelin sheaths (what coats the nerves), leading to demyelination (scarring). When the nerve coating is damaged, the nerves cannot conduct proper transmission or, again “as a manner of speak”, a short circuit takes place.

According to this recent study, EPA and DHA Omega-3 fatty acids are immune cell modulators and have been reported to decrease the pro-inflammatory signals, responsible for the recruiting of the immune cells in the development and the progression of MS, from 21.5% to 51.4%, depending on the concentration (intake) of Omega-3 in the blood.

In addition, other studies have concluded that the active lesions of multiple sclerosis contain large numbers of activated macrophages (immune cells), one of the culpable responsible for the demyelination (destruction of the nerves’ insulation) and that the myelin ingestion (destruction) by the immune cells is the unfortunate end-result of the body's intent to induce an anti-inflammatory response. (1,2,3)

Not only DHA (Omega-3) confers an anti-inflammatory benefit but also it is a key component in the structure, as well as the production of myelin sheaths from Plasmalogens. Without DHA (Omega-3) myelin sheaths (nerve coatings) would not be formed. (4)

Furthermore, studies have shown that fibrin deposition is to regulate the onset of inflammatory demyelination (destruction of nerves' costings) and it has been demonstrated that genetic or pharmacologic fibrin depletion ameliorates both clinical symptoms and the severity of Multiple Sclerosis. Data has identified fibrin as a major blood-derived component in demyelination. (5)

Tissue plasminogen activator (TPA) is a protein involved in the breakdown of fibrin and studies on the effects of a diet rich in Omega-3 PUFA resulted in a breakdown of fibrin by 21 +/- 5%. (6)

In conclusion, Nutri-Med Logic Corp agrees with the study done by the Department of Neurology, Oregon Health & Science University and the Department of Veterans Affairs Medical Center, but adds that since the study highlighted Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA), two Omega-3 fatty acids, then a Balanced Omega-3, having 50% EPA, 50% DHA, without a doubt, should be the Omega-3 of choice for those looking for anti-inflammatory diet.

Nutri-Med Logic Corp is a producer of dietary supplements, including a Concentrated and Balanced Omega-3: having the same concentration of EPA and DHA, 50% - 50%.

DHA of Omega-3, also, offers beneficial properties mainly for the brain, nervous system and EPA of Omega-3, additionally, offers beneficial properties in cardiovascular system.

Nutri-Med Logic's products are Formulated Based on Nutritional Logic, made from the highest quality raw materials that are manufactured in pharmaceutical facilities, encapsulated in pharmaceutical facilities and, also, packaged in pharmaceutical facilities.

It must be noted that the studies, sources or statements, above and below, have not been evaluated by The FDA and, thus, one should not relate the cause of any diseases, stated herein, to lack of Omega-3 dietary supplementation; nor equate its supplementation to prevention, treatment or cure.

1. Neurochemical Research, VoL 15, No. 1, 1990, pp. 7-11.
2. Brain, 1988 111:1039-1059.
3. Brain 2006 129(2):517-526 (Oxford University Press)
4. J Psychiatry Neurosci. 2010 January; 35(1): 59–62
5. Preceeding of National Academy of Sceince. April 27, 2004 vol. 101 no. 17 6698-6703.
6. American Heart Journal. 1988 Nov; 116(5 Pt 1): 1201-6.

Media contact:
H.R. Zadeh
305 267 0225
contact(at)nutrimedlogic(dot)com

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