A New Study Suggests Certain Nutrients May Offer a Healthy Intervention In Premature Aging of Lungs

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A recently published study, investigating the relationship between chronic inflammation, cellular aging and premature aging of lungs, highlights the potential benefits of certain nutrients (polyphenols) in lung diseases such as COPD or Emphysema. Agreeing with this recent study, Nutri-Med Logic Corp adds that while polyphenols retain an inherent anti-oxidant (protective) property, the lungs are also protected against the constant oxidative challenge by non-enzymatic antioxidants, such as Glutathione and R-Alpha Lipoic Acid, two very important endogenous anti-oxidants, which also offer health benefits against oxidative stress premature aging.

A recently published study opens the discussion of the importance of nutrients as a therapeutic vehicle in lung diseases, such as COPD and Emphysema. Expanding on this study, Nutri-Med Logic Corp states that, while polyphenols in this new study are correctly suggested to retain potent anti-oxidant properties, capable of activating certain genes associated with aging, R-alpha Lipoic, an endogenous anti-oxidant, also retains similar suggested potent anti-oxidant properties, capable of interfering with premature cellular aging.

According to American Society for Clinical Nutrition (Proceedings of The International Conference on Polyphenols and Health), polyphenols are antioxidants, and since 1995 they have received more reviews and interest from nutritionists than antioxidant vitamins, carotenoids or minerals. (1)

In 2010, the Department of Environmental Medicine's Lung Biology and Disease Program, University of Rochester Medical Center, Rochester, NY, proposed that polyhenols, aside from having anti-oxidant properties, also, possess the potential ability to regulate metabolism, stress resistance, cellular survival, and cellular aging. (2)

In this recent study, University of Rochester Medical Center, states that COPD is, also, inflammaging (inflammatory disease associated with aging) and, further, since polyphenols possess the potential ability to regulate inflammation, due to their anti-oxidant and anti-inflammatory nature, promote cellular resistance to premature death via activating Sirt-1 (a gene associated with regulation of cellular aging), polyphenols offer promising therapeutic intervention for lung health.

Notable polyphenols are resveratrol, curcumin and catechins, found in red wine, turmeric and green-tea, respectively.

Not only the University of Rochester Medical Center but also many other equally prestigious institutes have suggested the potential benefits from nutrients such as polyphenols, due to their antioxidant, anti-inflammatory and anti-premature cellular aging potentials.

One other equally important nutrient is R-Alpha Lipoic, which has anti-oxidant properties that could surpass polyphenols, due to its hydrophilic and lipophilic ability (water and fat soluble), as well as its potential ability to neutralize free radicals in mitochondria (cellular energy plant).

Alpha Lipoic was used by Dr. Burton Burkson, The FDA principal investigator of Lipoic Acid for last 23 years, in the treatment of a patient with pancreatic cancer and liver metastases. Dr. Burkson credits Lipoic Acid for its ability to moderate NF-kB, a master switch of inflammation. As a parallel comparison, the recent study also suggests moderation of NF-kB by polyphenols.

Additionally the anti-aging properties of R-Alpha Lipoic acid was a component of supplements that got the attention of the National Cancer Institute (NCI) Division of Cancer Biology (DCB) as a popular combination of anti-aging and vitality formulaā€¯, as reported by National Toxicology program, National Institute of Environmental Health Sciences.

It has been suggested that dietary supplementation of R-Alpha Lipoic Acid (also known as R- Lipoic Acid), increases the production, as well as the cellular concentration, of glutathione, which decrease by age. Glutathione is perhaps the most potent internal anti-oxidant and its decline shifts the body toward oxidative stress and its inevitable consequences of cellular aging.

In Conclusion, Nutri-Med Logic Corp agrees with this recent study regarding the benefits of polyphenols. However, Nutri-Med Logic Corp adds that R-Alpha Lipoic is equally important as an endogenous anti-oxidant, and a vital co-enzyme in the production of energy, which a plethora of studies have suggested. Also, it is valuable for its multi-faceted benefits.

Nutri-Med Logic Corp. is a producer of dietary supplements, including a Pharmaceutical Grade R-Alpha Lipoic Acid, the dietary supplement of choice for the Diabetics, in Germany for more than 40 years.

Nutri-Med Logic Corp is also producer of a Natural, Balanced, Deodorized and Concentrated Omega-3, which is also a Pharmaceutical Grade Omega-3;

Producer of PolyEnylPhosphatidylCholine (PPC 425mg), an extract of soy and the recommended dietarty supplement for those with Fatty Liver and Alcoholic Liver Disease, in Europe for about 50 years;

Nutri-Med Logic's products are Formulated Based on Nutritional Logic, made from the highest quality raw materials that are manufactured in pharmaceutical facilities, encapsulated in pharmaceutical facilities and packaged in pharmaceutical facilities.

It must be noted that the studies, sources or statements above and below have not been evaluated by The FDA and, thus, one should not relate the cause of any diseases, stated herein, to lack of the dietary supplements, stated herein, nor equate their supplementation to prevention, treatment or cure.

1. American Journal of Clinical Nutrition, Vol. 81, No. 1, 215S-217S, January 2005
2. Arch Biochem Biophys. 2010 Sep 1;501(1):79-90


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H.R. Zadeh
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