QualityStocks News - International Stem Cell Corp. Congratulates Nobel Prize Winners

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Company praises efforts of professors and discusses its promising cellular reprogramming technology.

This technology provides an alternative to the existing cellular reprogramming methods and represents an enormous opportunity for ISCO to become a leader in the iPS field.”

QualityStocks would like to highlight International Stem Cell Corporation (OTCBB: ISCO), focused on the therapeutic applications of human parthenogenetic stem cells (hpSCs) and the development and commercialization of cell-based research and cosmetic products. ISCO's core technology, parthenogenesis, results in the creation of pluripotent human stem cells from unfertilized oocytes (eggs).

In the company’s news yesterday,

International Stem Cell Corp. applauded Sir John Gurdon and Dr. Shinya Yamanaka for securing the Nobel Prize in Physiology or Medicine. The team’s use of cellular reprogramming to create pluripotent stem cells has led to the development of induced pluripotent stem cells (iPS), which is now a major area of research. However, cellular reprogramming is currently accomplished by inserting genetic material, via a virus or otherwise, which raises serious safety concerns when developing treatments.

ISCO, in comparison, has developed a technology that could enable the creation of a new generation of iPS cells without these safety concerns. Unlike methods requiring the use of viruses or DNA constructs that may integrate into the genome, ISCO’s new method utilizes only proteins which are naturally eliminated once they have served their purpose.

“Overall, our new technology represents a level of control that is much finer than the multiple infections necessary for viral-based systems which cannot be turned off and where the dosage level cannot be modulated,” stated Dr. Ruslan Semechkin, Vice President and head of ISCO’s Research and Development. “Moreover, ISCO’s method can be used not only to reprogram somatic cells to become stem cells, but also transform stem cells into somatic cells. This technology provides an alternative to the existing cellular reprogramming methods and represents an enormous opportunity for ISCO to become a leader in the iPS field.”

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