Studies in Anxiety and Depression Point to Age-Associated Benefits of Omega-3

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A new study has resulted in significant finding regarding Depression, Anxiety and inflammation in older population. More specifically, the inflammatory bio-marker PAI-1 is suggested to be a good indicator of Remitted Depression in the older population. Nutri-Med Logic Corp adds, while PAI-1 is a good indicator of remitted depression in the old, but PAI-1 is also an indicator of hypertension risk and coronary artery disease in the older adults as well as a good indicator of mental stress, a precursor to anxiety in younger adults.

A newly published study by the School of Medicine, Adelaide University, Adelaide, Australia, suggests inflammatory markers, more specifically, the marker PAI-1 is associated with remitted depression but not with the symptom of anxiety in the older population. Nutri-Med Logic Corp adds that PAI-1 is also an indicator of mental stress, which is the precursor to anxiety in the younger population, as well as hypertension and coronary artery disease in the older population.

As to PAI-1 and cardiovascular risk, DR. John Laragh, a Professor of Medicine in Cardiothoracic Surgery and Director of the Cardiovascular Center at The New York Presbyterian Hospital-Weill Cornell Medical Center, more than three decades ago discovered the relationship between stress system and malignant hypertension, in which the body’s ability to dissolve clots is inhibited by PAI-1.

Later in time, studies by Veterans Administration Medical Center, Gainesville, concluded that supplementation of Omega-3, in three weeks, resulted in a decrease of PAI-1 levels by 21 +/- 5% and such reduction in PAI-1 also correlated with a reduction in blood triglycerides (American Heart Journal. 1988 Nov; 116(5 Pt 1):1201-6.)

As to PAI-1 and mental stress, overwhelming number of studies have shown a strong correlation between higher levels of stress and increased levels of PAI-1. In particular, blood samples taken before and after a battery of psychological questionnaires, to create mental stress, revealed a strong relationship between mental stress and PAI-1, in which there was a decrease in certain tissue molecules that become inactivated due to an increase in PAI-1 (A decrease in tPA-PAI-1 complex). Eur J Appl Physiol. 2000 Nov;83(4 -5):344-8.

The dietary intervention of Omega-3 in reducing stress has been well studied, most notably in a recent study by National Institute on Alcohol Abuse and Alcoholism of National Institutes of Health (NIH) and Uniformed Services University of the Health Sciences (USUHA), which has sought to incorporate Omega-3 into the diet of the U.S. military, especially those in deployment situation.

Additionally, The National Center for Complementary and Alternative Medicine (NCCAM) of The National Institutes of Health (NIH) also concluded, in a recent report, that an anti-inflammatory diet consisting of Omega-3 reduced the symptoms of Anxiety in the young and healthy subjects, not yet diagnosed with the disorder.

In conclusion, Nutri-Med Logic Corp states that the findings of overwhelming number of studies relating to PAI-1, mental stress, anxiety and hypertension highlight the importance of Omega-3 dietary intervention, from young to old. Omega-3 polyunsaturated fatty acids not only offer substantial benefits for the cardiovascular health of the older population but also confer beneficial or protective properties for reducing anxiety in young adults, even those not yet diagnosed with the disorder.

The diverse benefits of Omega-3 in cardiovascular or nervous system arises from two important polyunsaturated fatty acids: EPA Omega-3 fatty acids with broad anti-inflammatory application in cardiovascular system and DHA Omega-3 fatty acids with broad anti-inflammatory and protective application in the brain and nervous system. Low levels of DHA Omega-3 fatty acids have also been associated with higher levels of mental stress and aggression.

Nutri-Med Logic Corp is the producer of the Natural, Balanced, Deodorized, Concentrated & Pharmaceutical Grade Omega-3.

Nutri-Med Logic Corp is also a producer of dietary supplements such as a Pharmaceutical Grade R-Alpha Lipoic Acid, a potent anti-oxidant and the dietary supplement of choice for the Diabetics, in Germany for decades;

Producer of PolyEnylPhosphatidylCholine (PPC 425mg), an extract of soy, a pure and effective dietary source of choline and the recommended dietary supplement for those with Fatty Liver and Alcoholic Liver Disease, in Europe for decades.

Nutri-Med Logic Corp invites you to visit its News Archives and Review its News Releases on other potential benefits of Omega-3 and What is Omega-3 Good For.

Nutri-Med Logic's products are Formulated Based on Nutritional Logic, made from the highest quality raw materials that are manufactured in pharmaceutical facilities, encapsulated in pharmaceutical facilities and packaged in pharmaceutical facilities.

It must be noted that the studies, sources or statements above have not been evaluated by The FDA and, thus, one should not relate the cause of any diseases, stated herein, to lack of the dietary supplements, stated herein, nor equate their supplementation to prevention, treatment or cure.

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H.R. Zadeh
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