Diet May Play a Key Role, as a Turning Point, in Most Alzheimer’s Cases

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A newly published report states that while there are 73,000 published papers on Alzheimer’s Disease, less has been relative to why people get Alzheimer’s and what may be done to avoid it and makes compelling recommendations, which could lower the prevalence of this disease. Nutri-Med Logic Corp, agreeing with this report, adds while the report correctly addresses some of the key nutritional factors that cause neuro-degeneration in Alzheimer's but pro-inflammatory diet is also a key contributing cause.

A new report by University of Texas at Austin, Austin, TX, states that compelling evidence links Alzheimer to multifactorial risk disorder resulting in low blood circulation to brain (chronic brain hypo-perfusion) during advanced aging. Nutri-Med Logic Corp adds that while the factors mentioned in this report, more specifically, micro-nutrients, trace metals, lipids and pro-oxidants are all associated with the diet but overwhelming number of studies have also pointed to excess pro-inflammatory nutrients, as a key and contributing factor in the development and progression of this diseases.

The study by the University of Texas states that two decades of research and over 73,000 research papers has not resulted in a significant progress as to why people get Alzheimer and what could be done to avoid it. Nutri-Med Logic Corp adds that The University of Texas correctly attempts to shift the focus from “how to treat the symptoms” to “how to avoid the key causes” of the Sporadic Alzheimer.

According to National Alzheimer’s Council, Sporadic Alzheimer constitutes 90-95% of Alzheimer’s cases.

The report blames, in part, micro-nutrients, trace metals, lipids and pro-oxidants as being involved in the development of oxidative stress and neuro-degeneration, in the presence of low blood flow to the brain, seen in Sporadic Alzheimer.

Department of Physiological Science, University of California at Los Angeles has studied the relationship between a diet high in saturated fat (lipids) and the decrease in the levels of Brain-Derived Neurotrophic Factor (BDNF), which suggests a high-fat diet affects cognitive function.

According to the University of Miami, BDNF is essential for many functions such as neuronal growth and maturation. University of Miami further states that boosting BDNF is thought to be beneficial in several human disorders, including Alzheimer’s disease. (Nature Biotechnology, March 25, 2012.)

Studies have successfully incorporated the use of anti-oxidants as a mean to combat the drop in BDNF levels, due to oxidative stress caused by the high-fat diet. (Eur J Neurosci. 2004 Apr;19(7):1699-707.)

Attempts to increase the BNDF levels either through medication, gene therapy or simply through diet (anti-oxidants) coincides with the finding of the University of Texas, which points to lipids (fat) and pro-oxidant (causing oxidative stress) as two of the key factors.

While the high-fat diet is a matter of choice, factors such as metals and pro-oxidants are mainly counteracted by an internal antioxidant called Glutathione, which its levels drops by age. None-the-less, Glutathione can be increased through diet, more specifically through supplementation of a nutrient called R-Alpha Lipoic.

Additionally, several studies have determined that the structure within the neuronal cell membrane bilayer, more specifically Omega-3 (anti-inflammatory) / Omega-6 (Pro-inflammatory) ratio, is associated to detrimental or beneficial effects in Alzheimer’s.

In animal studies, Omega-6 (abundant in red meat) resulted in significantly higher secretion of Abeta-40 and Abeta-42 proteins (both implicated in Alzheimer’s) compared to Omega-3 diet and that an early-onset of Alzheimer's has corroborated with the in-vitro findings that lower levels of Abeta in the brain were associated with low fat-diet enriched in Omega-3. J. of Biol. Chem. 2010 Oct 22. (Epub).

In conclusion, Nutri-Med Logic Corp, agreeing with University of Texas study, adds that in addition to the nutritional factors mentioned in the study, pro-inflammatory nutrients also play a key and fundamental role in the development and the progression of the Alzheimer’s.
Nutri-Med Logic Corp is the producer of the Natural, Balanced, Deodorized, Concentrated & Pharmaceutical Grade Omega-3. Omega-3 is the most effective anti-inflammatory nutrient.

Nutri-Med Logic Corp is also a producer of dietary supplements such as a Pharmaceutical Grade R-Alpha Lipoic Acid, a potent anti-oxidant and the dietary supplement of choice for the Diabetics, in Germany for decades;

Producer of PolyEnylPhosphatidylCholine (PPC 425mg), an extract of soy, a pure and effective dietary source of choline and the recommended dietary supplement for those with Fatty Liver and Alcoholic Liver Disease, in Europe for decades.

Nutri-Med Logic Corp invites you to visit its News Archives and Review its News Releases on other potential benefits of Omega-3 and What is Omega-3 Good For.

Nutri-Med Logic's products are Formulated Based on Nutritional Logic, made from the highest quality raw materials that are manufactured in pharmaceutical facilities, encapsulated in pharmaceutical facilities and packaged in pharmaceutical facilities.

It must be noted that the studies, sources or statements above have not been evaluated by The FDA and, thus, one should not relate the cause of any diseases, stated herein, to lack of the dietary supplements, stated herein, nor equate their supplementation to prevention, treatment or cure.

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H.R. Zadeh
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