The Science of Eye Misting: A New Approach to Dry Eye and Tear Film Dehydration

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Analysis of a Breakthrough Discovery for Dry Eyes from Sharon Kleyne, Founder of Bio-Logic Aqua Research.

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Ophthalmologists have long known that the primary symptom of dry eye disease is loss of natural water in the tear film (which is 99% water). For decades, discovery of an effective and comfortable way to replace lost tear film water had eluded researchers - until eye health advocate Sharon Kleyne invented the world's first all-water personal hand-held eye humidifying device that applies natural water in the form of an ultra-fine eye mist.

"Dry eye symptoms are the primary complaint of 80% of Ophthalmology patients in the United States," says Mrs. Kleyne. "As the global dry eye crisis worsens, personal eye humidifiers could become as indispensable to daily life as cell phones and toothbrushes."

In a recent interview, Sharon Kleyne discussed the research that led to her discovery, and the significance to dry eye patients. Mrs. Kleyne is host of the Sharon Kleyne Hour Power of Water syndicated radio show and founder of Bio-Logic Aqua Research.

According to Sharon Kleyne, the problem for researchers had been that you simply cannot replace lost tear film water by splashing water into your eyes. The reason is that the water's "osmolarity" (a function of mineral content) could cause painful "osmotic shock." Conjunctival and corneal epithelial cells on the eye's surface require the tear film's osmolarity to remain within a narrow range to maintain health and comfort. Osmotic shock can occur when the osmolarity of the tear film, or of any substance applied to the eyes (incliding water), falls significantly outside that range (Gilbert, 1978).

Sharon Kleyne discovered that osmotic shock can be virtually eliminated by using a nearly mineral free natural water and by applying the water as an ultra-fine eye mist. The pure water replaces the lost tear film water and overcomes the potential for osmotic shock by diluting the tear volume with exquisitely small microdroplets (Mathers, 1999).

Mrs. Kleyne was able to engineer the diameter of the mist droplets to within a 40-60 micron (millionths of a meter) range. When these microdroplets land on the ocular surface, they pass directly through the overlying lipid (oil) layer and dilute the underlying water layer without washing away normal tear constituents. The eye mist application canister invented by Mrs. Kleyne delivers 1-2 microliters (millionths of a liter) per square centimeter per second at fourteen inches from the face. Since the average exposed ocular surface area is 2 square centimeters, this results is 2 microliters per second to the eye.

"In 1 to 2 seconds," Mrs. Kleyne concludes," the tear volume can be diluted sufficiently to restore normal osmolarity (Mathers, 2005) (Method and Kit, 2009).

Mrs. Kleyne's eye mist application relieves dry eye by restoring the tear film's normal surface osmolarity and by removing noxious materials from the tear film. By restoring the surface to a state of health, according to Mrs. Kleyne, there should also be a beneficial effect on the lacrimal gland and down-regulation of the inflammatory effects of dry eye (Mathers, 2005).

The Sharon Kleyne Hour Power of Water, is sponsored by Bio-Logic Aqua Research, whose Nature's Tears® EyeMist® is the only all-natural, all water patented eye humidifying device that instantly supplements lost natural tear film water. Nature's Tears® EyeMist® is available at http://www.BioLogicAqua.com, Amazon.com, drugstore.com and selected drugstores nationwide.

The website for the Sharon Kleyne Hour Power of Water radio show (http://www.SharonKleyneHour.com) contains archived on-demand replays and printable summaries of Sharon Kleyne's interviews with leading eye health experts. The syndicated show is broadcast live Mondays at 10 a.m., PST/PDT, on Voice America/World Talk Radio, Green Talk Network and Apple iTunes. Also visit http://www.naturestears.com, whatistheeye.wordpress.com, "Nature's Tears EyeMist" on Facebook and "Bio-Logic Aqua" on Twitter.

Sources:
Gilbert, JP, "Osmolarity of tear film microvolumes in keratoconjunctivitis sicca," Archives of Ophthalmology, 1978.
Mathers, W, MD, Tear Film and Treatment of Dry Eye Disease, RxSchools.com, 200
Mathers, W, MD, Dry Eye Relief in a Unique Application, Vision Care Product News, 1999.
"Method and Kit for Moisturizing the Surface of the Eye," US patent 7,524,511B, 2009

© 2012 Bio-Logic Aqua Research

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Mikaylah Roggasch
Bio Logic Aqua Research-Rogue Media
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