Sleep-Disordered Breathing is Linked to Inflammation, Women Carrying a Higher Risk than Men

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In a recent study of large multi-ethnic sample of US adults, the markers of Sleep-Disordered Breathing had positive associations with the presence of CRP levels, an inflammatory marker. The study found that the disorder was more present in women and postmenopausally women were 2.6 times more likely to develop the disorder than perimenopausally women. Agreeing with this study, Nutri-Med Logic Corp adds, when taking into account the results of this study and the reduced estrogen levels (an anti-inflammatory hormone) at menopause together with the fluctuating estrogen levels in the studies of the menstrual cycle and sleep apnea, anti-inflammatory nutrients offer a viable dietary intervention.

In a large recent multi-ethnic study of US adults, the markers of Sleep-Disordered Breathing (SDB), including short sleep duration (less than 7 hours), long sleep duration (more than 7 hours), occasional or frequent snoring or snorting (2 night/week), and daytime sleepiness (more than1/month) had positive associations with the presence of CRP (an inflammatory agent) and examining the association between Sleep-Disordered Breathing and inflammation (CRP) by gender, there was only a weak association in men but significant association was found in women.

The study also states that when utilizing the Wisconsin Sleep Cohort Study of 907 but limiting the analysis to 589 women participants, Sleep-Disordered Breathing was 2.6 times more likely to occur postmenopausally than perimenopausally.

CRP (C-Reactive Protein) is an inflammatory molecule produced by liver, as a part of immune assisting molecules (compliment system), which carry inflammatory consequences. CRP is also considered a biological marker of cardiovascular disease. The associations between Sleep-Disordered Breathing and CPR (inflammation) together with the higher occurrence of Sleep-Disordered Breathing in postmenopausal women indicate that postmenopausal women are exposed to higher levels of inflammatory agents due to reduced estrogen, an anti-inflammatory hormone.

Studies have shown that the drop in estrogen during and after menopause is associated with increased production of many inflammatory agents and, additionally, according to University of Maryland Medical Center states, after menopause, women lose the protective (anti-inflammatory) effects of estrogen and are at increased risk for osteoporosis and heart disease.

Moreover, according to American Journal of Respiratory and Critical Care Medicine, women upper airway resistance was greater and there were more frequent obstructive events during the luteal phase (Low estrogen) of the menstrual cycle. (Am. J. Respir. Crit. Care Med. Nov 1, 2009 vol. 180 no. 9 909)

While hormone (estrogen) replacement therapy is always a viable option to increase estrogen levels and benefit from its anti-inflammatory properties but anti-inflammatory nutrients also offer many beneficial properties.

University of Maryland Medical Center also states that women who are at greater risk of heart disease after menopause may want to ask their doctor whether they should take a fish oil or simply increase the amount of fish they eat. The American Heart Association recommends having at least two servings of fish per week. Fish oil / fish are both a good source of Omega-3 Fatty Acids.

Omega-3 is the most effective and potent anti-inflammatory nutrient.

In conclusion, Nutri-Med Logic Corp agrees with this study and adds the association of CPR (inflammatory marker) and higher occurrence of Sleep-Disordered Breathing in postmenopausal women (2.6 times higher) is indicative of a drop in the biological anti-inflammatory hormones. Nutri-Med logic Corp also adds that Omega-3 is an effective and potent anti-inflammatory nutrient, highly beneficial for overall health as well as moderating inflammation.

Nutri-Med Logic Corp is the producer of the Natural, Balanced, Deodorized, Concentrated & Pharmaceutical Grade. Omega-3 is the most effective anti-inflammatory nutrient.

Nutri-Med Logic Corp is also a producer of dietary supplements such as a Pharmaceutical Grade R-Alpha Lipoic Acid (the natural type of Lipoic Acid), a universal anti-oxidant and the dietary supplement of choice for the Diabetics, in Germany for decades;

Producer of PolyEnylPhosphatidylCholine (PPC 425mg), an extract of soy, a pure and effective dietary source of choline and the recommended dietary supplement for those with Fatty Liver and Alcoholic Liver Disease, in Europe for decades.

Nutri-Med Logic Corp invites you to visit its News Archives and Review its News Releases on other potential benefits of Omega-3 Fatty Acids

Nutri-Med Logic's products are Formulated Based on Nutritional Logic, made from the highest quality raw materials that are manufactured in pharmaceutical facilities, encapsulated in pharmaceutical facilities and packaged in pharmaceutical facilities.

It must be noted that the studies, statements or sources above have not been evaluated by The FDA and, thus, one should not relate the cause of any diseases, stated herein, to lack of the dietary supplements, stated herein, nor equate their supplementation to prevention, treatment or cure.

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H.R. Zadeh
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