New Research on Non-Invasive Heart and Cancer Imaging Reported in Journal of Biomedical Optics

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Advances in non-invasive technologies for imaging breast, heart, and other tissues are featured in a special section on Medical Imaging Using Diffuse Optics in the Journal of Biomedical Optics published this month by SPIE. Applications include non-invasive methods for testing for breast cancer and monitoring of heartbeat arrhythmias such as flutter and fibrillation.

subject measurement with DOSI instrument

A handheld device is part of a DOSI (diffuse optical spectroscopic imaging) system developed for non-invasive medical imaging at the University of California, Irvine. Copyright SPIE 2012.

Papers cover applications such as MRI for a non-invasive, portable test for breast cancer, and OCT for monitoring of heartbeat arrhythmias such as flutter and fibrillation.

New research on non-invasive technologies for imaging breast, heart, and other tissues is published by SPIE, the international society for optics and photonics, in a special section on Medical Imaging Using Diffuse Optics in the July issue of the Journal of Biomedical Optics.

Papers cover advances such as using molecular resonance imaging (MRI) for a non-invasive, portable test for breast cancer, optical coherence tomography (OCT) for monitoring of heartbeat arrhythmias such as flutter and fibrillation, and other biomedical applications of diffuse optics imaging technologies.

The new special section on biophotonics topics is the latest in a series published every two years in the Journal of Biomedical Optics in conjunction with the biennial Biophotonics Graduate Summer School on the island of Ven, Sweden. The special section reflects core topics of the school, which is organized by special section guest editors Stefan Andersson-Engels (Lund University) and Peter Andersen (Technical University of Denmark). School participants and other researchers submit manuscripts for consideration.

“We are pleased to include in this year’s special section a very interesting open access tutorial paper on medical imaging using diffuse optics from the Tromberg group at University of California, Irvine,” Andersen said.

“The invited review paper belongs to a series of tutorial review papers from each biennial school that provide high-level educational material for the benefit of the scientific community and, in addition, fulfill our own motivation for creating the school in the first place,” Andersson-Engels said. “This article is followed by nine high-quality original articles covering diffuse optics and OCT.”

Among noteworthy papers are:

  •     “Molecular imaging of water binding state and diffusion in breast cancer using diffuse optical spectroscopy and diffusion weighted MRI,” by So Hyun Chung (University of Pennsylvania), Hon Yu and Min-Ying Su (University of California, Irvine), and Albert Cerussi and Bruce Tromberg (Beckman Laser Institute).
  •     “Tissue surface as the reference arm in Fourier domain optical coherence tomography,” by Nikola Krstajić (University of Edinburgh) and Christian Tom Brown, Kishan Dholakia, and Mario Ettore Giardini (University of St. Andrews).
  •     “Quantification of fiber orientation in the canine atrial pacemaker complex using optical coherence tomography,” by Christina Ambrosi, Vadim Fedorov, Richard Schuessler, and Igor Efimov (Washington University) and Andrew Rollins (Case Western Reserve University).

View the table of contents and download papers from the SPIE Digital Library.

SPIE, a long-time sponsor of the biophotonics graduate summer school, in January 2012 took on the role of primary international society sponsor.

“The main purpose with the summer school is to provide education within biophotonics for students and young scientists at the highest international level,” Andersson-Engels said. “Our aim is to attract internationally renowned researchers as lecturers who will attract the most talented young researchers worldwide in the field of biophotonics.”

About SPIE

SPIE is the international society for optics and photonics, a not-for-profit organization founded in 1955 to advance light-based technologies. The Society serves nearly 225,000 constituents from approximately 150 countries, offering conferences, continuing education, books, journals, and a digital library in support of interdisciplinary information exchange, professional growth, and patent precedent. SPIE provided over $2.7 million in support of education and outreach programs in 2011.

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