Solving the Impedance Mismatch between Patient Sample and POC Diagnostic systems

Knowledge Foundation - Integrating SAMPLE PREPARATION 2012 – October 18-19, 2012 – Baltimore, MD

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Boston, MA (PRWEB) August 30, 2012

Dr. John Carrano of Paratus Diagnostics will present on "Solving the Impedance Mismatch between Patient Sample and POC Diagnostic systems" at the upcoming Integrating SAMPLE PREPARATION 2012 Conference set to take place on October 18-19, 2012 in Baltimore, MD. In this paper we posit that in order to realizepragmatic point-of-care medical diagnostic devices capable of meeting therigorous requirements of CLIA waiver, that one must solve the inherent"impedance mismatch" between the clinical acquisition of a human patient sampleand its delivery to the POC Dx system or device. We work from the assumptionthat specimen acquisition from the patient must follow standard clinicalpractice, and that the POC system (e.g. "device") will be designed to follow ayet to be determined international interface standard (similar in principle tothe now ubiquitous Luer-Lock standard). We will present a design concept for a"specimen delivery system" and the associated proposed interface standard,along with experimental data from preliminary rapid prototype models,

Integrating SAMPLE PREPARATION – Techniques & Applications Conference, a part of the Knowledge Foundation’s Sample Prep Conference Series - an internationally recognized meeting for experts in sample preparation technologies for detection, identification, diagnostics and analysis of biomedical, biological and chemical agents, substances and threats in point-of-care, laboratory and field settings will explore the latest R&D developments, ready-to-market technologies, and their applications by exploring the following topical areas:

-Increasing recognition of sample preparation as the biggest challenge and technology development area in biomed, biodefense and pharma
-Application driven sample preparation techniques development
-Critical role of sample prep in early diagnostics
-Rapid sample-to-sequence techniques
-Sample preparation as a separate system vs. an integrated module approach
-End-user prospective for biodetection and sampling technologies and devices
-Is remote detection without sample preparation a viable option?
-Major challenges of sample preparation system integration (front end) approach
-Recent advances standalone sample preparation systems technology development and application
-Point-of-care diagnostics applications for virus/pathogen/ threat sampling, detection and analysis
-Food, water, air, and environmental sampling
-Alternative and disruptive approaches to sample preparation and applications

Distinguished Speakers Faculty
-John C. Carrano, PhD, Paratus Diagnostics, LLC
-Michael Connolly, PhD, Integrated Nano-Technologies, LLC
-Dennis W. Harris, DPhil, IntegenX, Inc.
-Claudia Gärtner, PhD, microfluidic ChipShop GmbH
-David Cohen, PhD, Advanced Liquid Logic
-Zhenyu Li, PhD, The George Washington University
-Latarsha Carithers, PhD, National Cancer Institute / National Institutes of Health
-John Jakupciak, PhD, Cipher
-Robert Classon, Shimadzu Scientific Instruments
-Yossi Manor, Central Virology Laboratory, Sheba Medical Centre, Israel
-Donn Zuroski, FOSC, Emergency Response Section, Region 9, US Environmental Protection
-Martin Hegner, PhD, Centre for Research on Adaptive Nanostructures and Nanodevices, Trinity College Dublin, Ireland
-Sergey A. Dryga, PhD, nanoMR, Inc.
-Bee-Na Lee, PhD, Beckman Coulter
-Byron Brehm-Stecher, PhD, Rapid Microbial Detection and Control Laboratory, Iowa State University
-Teshome Yehualaeshet, DVM, PhD, College of Veterinary Medicine, Tuskegee University
-Andy Page, InnovaPrep LLC
-Jeffrey A. Hickey, PhD, ZyGEM, Inc.
-Vanessa Yu, PhD, Bertin Corporation
-Bruce Irvine, Claremont BioSolutions LLC

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The Knowledge Foundation integrates scientific ingenuity and real-world applications by fostering collaborative research at the rapidly changing intersection of science and business. Known for providing members of its Technology Commercialization Alliance with direct and unbiased state-of-the-art scientific information, the Knowledge Foundation is uniquely qualified to provide wider exposure for important developments in the emerging fields of alternative energy, nanotechnology, and chemical & biological detection technologies.

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