Automated Sample Preparation and Analysis for Next-Generation Sequencing by Sandia National Labs To Be Presented at Knowledge Foundation’s Sample Prep 2013 Conference

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Sample Prep 2013

Industry leaders from around the world will convene in San Diego, CA for the Knowledge Foundation’s 7th Sample Prep 2013 conference which will take place at the San Diego Hilton & Resort on May 9 – 10. One of the many anticipated presentations will include Numrin Thaitrong, PhD, of Sandia National Labs as they present “No-Spin Sample Preparation for Cartridge-Format Point-of-Care HIV Viral Load Testing”

Presentation Abstract:

“Automated Sample Preparation and Analysis for Next-Generation Sequencing”

Numrin Thaitrong, PhD, of Sandia National Labs

Thorough characterization of next-generation sequencing library is a required process in the sample preparation workflow. However, this built-in quality control feature is currently not available for small-scale library construction platforms. We have developed an integrated droplet-based digital microfluidics (DMF) architecture with capillary interface to handle sub-microliter sample processing and analysis. The platform providing size distribution and quantization of the library can be coupled to the existing modular DMF “hub” to automate start-to-finish library construction. This presentation will be given by Numrin Thaitrong, PhD, of Sandia National Labs at Sample Prep 2013.

Sample Prep 2013 Program topics will include:

  • Robust methodologies for sample collection, (pre-)concentration, lysis, and target extraction
  • Critical role of sample prep in early diagnostics
  • Rapid sample-to-sequence techniques
  • Point-of-care sampling, detection and analysis
  • Sample preparation with micro- and nano fluidics
  • Robust sampling methodologies (automation, high-throughput, combinatorial approach in sample prep)
  • Alternative amplification techniques for sensitive sample prep
  • End-user prospective for biodetection and sampling technologies and devices
  • Alternative and disruptive approaches to sample preparation and applications
  • Field-ready devices: compatibility/reliability/scalability
  • Target enrichment and background depletion techniques
  • Isolation of dilute objects on cell and molecular levels
  • Immiscible phase purification
  • Novel methods of extraction from tough (non-filterable) matrices
  • Nucleic acid and protein based sample prep for next generation sequencing
  • Nanotechnology and miniaturization challenges for sample preparation
  • Standardization and regulatory issues in sample preparation across different applications

Distinguished Speaker Faculty:
-Charles Young, PhD, The Johns Hopkins University
-Richard Allen, PhD, Luminex Corporation
-John C. Carrano, PhD, Paratus Diagnostics, LLC
-Forest L. Rohwer, PhD, San Diego State University
-Sarah Fakih, PhD, QIAGEN GmbH, Germany
-Season Wong, PhD, AI Biosciences, Inc.
-Michael J. Heller, PhD, University of California San Diego
-Martin McDonnell, PhD, Defense Science and Technology Laboratory - DSTL Porton Down, United Kingdom
-Alexis Sauer-Budge, PhD, Fraunhofer USA
-Gregory Auner, PhD, Wayne State University
-Hafsa Korri-Youssoufi, PhD, University Paris-Sud, France
-Shan Gao, PhD, Wave 80 Biosciences, Inc.
-David Wright, Wi Medical Device Development, Inc.
-Mark W. Eshoo. PhD, Ibis Biosciences Inc., an Abbott Company
-Mark Tondra, PhD, Diagnostic Biosensors
-Patrick Broyer, PhD, bioMérieux SA, France
-Andy Page, InnovaPrep LLC
-Numrin Thaitrong, PhD, National Center for Genetic Engineering and Biotechnology / Sandia National Labs
-Marek Smieja, MD, PhD, McMaster University, Canada
-Bruce Irvine, Claremont BioSolutons
-Vasco Liberal, PhD, Biomatrica, Inc.

About The Knowledge Foundation
The Knowledge Foundation integrates scientific ingenuity and real-world applications by fostering collaborative research at the rapidly changing intersection of science and business. Known for providing members of its Technology Commercialization Alliance with direct and unbiased state-of-the-art scientific information, the Knowledge Foundation is uniquely qualified to provide wider exposure for important developments in the emerging fields of alternative energy, nanotechnology, and chemical & biological detection technologies.

Contact:
The Knowledge Foundation
2193 Commonwealth Ave, Suite 398
Boston, MA 02135-3853
Phone: (617) 232-7400
Fax: (617) 232-9171
Email: custserv(at)knowledgefoundation(dot)com
Website: http://www.knowledgefoundation.com

Media Contact:
Matt DiCecca
Conference Marketer
(617) 232-7400 ext. 203
Email: mdicecca(at)knowledgefoundation(dot)com

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