March Homeostasis: Publius’ Go Endo-Cannabinoid Update ~ New on the Bryan William Brickner Blog

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March springs forth and Publius celebrates the human body’s endo-healing power with four homeostatic updates from the National Institutes of Health (PubMed). Today’s cannabinoid system research highlights: late-onset Alzheimer’s disease, an anti-epileptogenic approach, toll-like receptors mediating immune responses, and the endocannabinoid 2-AG and its rheumatoid arthritis regulatory functions.

The Cannabis Papers by Publius

Health is within and learning of cannabinoids and endo-healing bodies … is good.

“Health is an endo thing, from within,” opened Bryan W. Brickner, “and as we learn more about the cannabinoid system … we learn it’s where health begins.”

In March Homeostasis: Publius’ Go Endo-Cannabinoid Update ~ new on the Bryan William Brickner Blog, homeostatic health, or endo-healing, is celebrated. Publius, of The Cannabis Papers: A citizen’s guide to cannabinoids (2011), showcases four 2015 National Institutes of Health (PubMed) cannabinoid system (CS) articles discussing: cannabinoids in the treatment of late-onset Alzheimer’s disease (LOAD), an anti-epileptogenic approach based on the endo 2-AG, toll-like receptors mediating immune responses via the CS, and rheumatoid arthritis and the multiple regulatory functions of the CS – with the endo 2-AG highlighted.

“There is a lack of effective treatments for late-onset Alzheimer's disease,” Brickner noted, “and today’s CS overview looks at the potential of cannabinoids in the treatment of LOAD and related neuropsychiatric symptoms in older people.”

“The kindling epilepsy science notes a CS role in the inhibition of enzyme degradation,” Brickner continued, “and reports a promising strategy to selectively activate CB1 receptors via 2-AG modulation for a novel anti-epileptogenic approach.”

“The science on toll-like receptors,” followed Brickner, “shows how the CS mediates innate immune responses that are critical to homeostasis and our response to injury.”

“The rheumatoid arthritis CS science,” Brickner added, “echoes homeostasis as well; this one notes a fundamental role for cannabinoids in inflammation.”

“Health is within,” Brickner closed, “and learning of cannabinoids and endo-healing bodies … is good.”

Brickner has a 1997 political science doctorate from Purdue University and is the author of several political theory books, to include: The Promise Keepers: Politics and Promises (1999), Article the first of the Bill of Rights (2006), and Shivitti: A Review of Ka-Tzetnik 135633’s Vision (2015). He also writes political fiction, such as the novella thereafter (2013), and is the publisher of The Cannabis Papers: A citizen’s guide to cannabinoids (2011) and The Bryan William Brickner Blog, a resource for the political science of constitutions and the biological science of receptors.

The Cannabis Papers is available at online retailers and for free by download.

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Bryan W. Brickner
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