Upland, CA, March 17, 2014 (PRWEB) March 14, 2014
Claremont BioSolutions, LLC today announced that the US Patent and Trademark Office has issued a foundational patent covering its SimplePrep™ micromotor‐based rapid sample preparation technology. The patent, US 8,663,974, describes devices that are used to prepare samples for DNA analysis using low-cost vibration motors that are repurposed from the cell phone industry. The miniature motors provide mechanical energy necessary to disrupt cell membranes of any cell type, even hard to lyse cells such as bacterial spores. The patent also describes similar devices that incorporate ceramic beads to both aid the lysis process and extract and purify the DNA/RNA released from the cells. The patented cartridges can be disposable and produce purified nucleic acids in less than five minutes.
Claremont BioSolutions CEO Gary Blackburn commented that “it is rewarding to see the patent office validate the novelty of this technology; we expect to use these devices in collaborations with diagnostics companies that want to incorporate a reliable, rapid, and inexpensive sample prep technology into point-of-care (POC) consumable cartridges.” He went on to say, “These devices are also attracting interest among companies that desire to implement tissue homogenization processing on robotic liquid handler platforms. This technology is the first real advance in the sample prep industry that has largely relied on decades-old methods and devices since the 1980’s.”
The company has commercialized several single-use devices for lysing cells, extracting and purifying nucleic acid, and homogenizing tissue samples on its website (http://www.claremontbio.com). “We are developing a simple instrument that will process up to eight cartridges simultaneously in less than five minutes, with each cartridge delivering the purified DNA to an Eppendorf tube, ready for analysis,” commented Robert Doebler, President and co-founder of ClaremontBio. “Our customers are surprised that sample prep can be so simple and rapid, especially in a completely disposable device that doesn’t require a centrifuge or any other lab equipment -- just a AAA battery pack and a pipettor or syringe is all that is required.”
About Claremont BioSolutions.
Claremont BioSolutions (http://www.ClaremontBio.com) is a privately held, emerging growth technology company specializing in disposable devices that provide solutions to what is recognized as the “bottleneck” of DNA diagnostics – sample preparation. The company has developed proprietary devices which employ micromotors to perform very efficient mechanical cell lysis and DNA purification.
Gary Blackburn, Ph.D.
Chief Executive Officer
Claremont BioSolutions, LLC
Phone: (626) 825‐6962
Fax: (909) 946‐1132
Address: 1182 Monte Vista, Ave., Suite 11
Upland, CA. 91786