Monitor Granule Growth in Process with the FBRM® C35
METTLER TOLEDO announces the launch of the FBRM® C35, designed to target granule size in real time.
Columbia, MD (PRWEB) October 1, 2008 -- Using probe-based FBRM (Focused Beam Reflectance Measurement) technology the FBRM® C35 enables formulation scientists and engineers to quickly associate particle system dynamics to processing conditions while with no sampling or sample preparation required. This allows for quick and thorough understanding and optimization of a high shear wet granulation, roller compaction, or fluidized bed granulation process.
With the new FBRM® C35, formulators and engineers can:
| | - Understand granulation - Monitor real-time changes in particle count and dimension during cohesive wet or dry particle processing and enable Quality by Design (QbD) throughout granulation development, scale-up, and manufacturing;
- Control batch to batch repeatability - Troubleshoot unexpected process changes to minimize batch failures, improve yield, and troubleshoot scale-up or technology transfer;
- Identify batch endpoint - Ensure consistent downstream particle flow, tableting, and dissolution;
- Ensure consistent measurements - A patented scraper keeps the probe window clean allowing the C35 to track particle agglomeration, compaction, and breakage even in the most cohesive particle conditions.
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METTLER TOLEDO FBRM® is the world leading Process Analytical Technology (PAT) for in situ particle characterization across the pharmaceutical and chemical industries.
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