Weight loss can generally affect gene expression in your children!
Park Ridge, IL (PRWEB) August 01, 2013
The increase in number of overweight children in the U.S. has as much to do with their genes as their exercise habits and diet. Some genetic differences recently revealed by researchers are rare; however, others are rather common, suggesting collaboration between genetics and environment. This could explain why some children develop obesity while others do not even when they share a similar upbringing.
A new study from The American Society for Aesthetic Plastic Surgery published on April 24th,2013 suggests that women who undergo weight loss surgery may obtain a genetic bonus for the health of their future children. Studies show that children born to mothers who had lost weight due to gastric bypass surgery had significant differences in genetics compare to their siblings who were born before their mother had the procedure. The genetic shifts were mostly seen as developments in the areas of the heart and inflammatory health for the children.
Researchers at the Karolinska Institutet in Sweden in April 2013 found that following weight loss surgery, genes related to metabolic health can be "restored to a healthy state," resulting in an overall improvement in metabolism. In other words, after surgery, the genes responsible for maintaining a healthy weight and burning calories may be enhanced.
When an individual goes through the weight loss of the operation, there are variations in the patient’s DNA adjustments that control gene expression in response to the change in environment. After surgery, the levels of these genes are restored to a healthy state, which mirrors weight loss and coincides with overall improvement in metabolism. Differences in DNA methylation (which firmly alters the expression of genes, controls glucose and fat metabolism are connected with obesity) is reversed after weight loss surgery.
“Weight loss or food consumption can generally affect gene expression through this mechanism,” notes Dr. Sam Speron board certified plastic surgeon and consumer advocate. “It is quite amazing to see the results of this study and it does make me wonder about what the limits are between the lifestyle choices we make and how these can change our actual DNA and the DNA of our children.”
Researchers also concluded that bypass surgery works not by restricting food intake physically but mostly through physiological effects. This alters appetite to minimize hunger and improve satiety and as well as increasing daily energy consumption.
Dr. Speron is the founder and medical director of Dr. Speron Plastic Surgery. He is board certified with the American Board of Plastic Surgery and an active member of both the American Society of Plastic Surgeons (ASPS) and American Society of Aesthetic Plastic Surgeons (ASAPS).
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