Cell Signaling Technology Discusses Challenges and Opportunities of Post-translational Modifications and Data-Independent Acquisitions in Educational Webinar

Share Article

In this webinar, which LabRoots will host October 30, participants will gain a better understanding of the relevance of assessing protein PTM isoforms based on PTM site localization.

Birgit Schilling, PhD Assistant Professor, Buck Institute for Research on Aging, Director of the Mass Spectrometry Core, Buck Institute; Adjunct Professor, USC.

Identification and quantification of post-translational modifications (PTMs) presents a unique challenge to proteomic studies. Often, PTMs feature low abundances, and many possible functionally distinct locations may exist within each protein. Although label-free data-independent acquisitions (DIA, or SWATH®Acquisition) have been extensively used for global proteomics workflows and quantification of proteins, so far there are only few studies applying DIA to study PTMS.

In this webinar, which is sponsored by Cell Signaling Technology, the speaker will present several DIA-PTM studies, specifically of phosphorylated as well as acylated proteins using different affinity-enrichment approaches. They will examine case studies specifically using Cell Signaling Technology affinity enrichment kits for our work (PTMScan® affinity enrichment kits for acetylation/succinylation and PTMScan® Direct Tyrosine and Serine/Threonine Kinases Reagents).

Participants will learn to use simultaneous affinity enrichment workflows by combining different PTM antibodies for ‘one-pot enrichment’ approaches, as well as the applications involving stable isotope labeled PTM-peptides.

The speaker for this event will be Dr. Birgit Schilling, an associate professor and director of the Mass Spectrometry Core at the Buck Institute for Research on Aging. Her research focuses on protein chemistry and modern mass spectrometric technologies to advance the field of Proteomics mainly in the context of Aging Research. She is directly involved in a wide variety of research projects, including neurodegenerative diseases, cancer, diabetes, molecular mechanisms of aging, and mass spectrometric method development that will benefit biological projects.

LabRoots will host the webinar on October 30, 2018, beginning 10 a.m. PDT, 1 p.m. EDT. To learn more about this event and the speaker, discover the continuing education credits offered, or to register for free, click here.

About Cell Signaling Technology
Cell Signaling Technology is a private, family-owned company, founded by scientists and dedicated to providing high-quality research tools to the biomedical research community. The company’s employees operate worldwide from its US headquarters in Massachusetts, and offices in the Netherlands, China, and Japan.

About LabRoots
LabRoots is the leading scientific social networking website, which provides daily scientific trending news, as well as produces educational virtual events and webinars, on the latest discoveries and advancements in science. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning, and is a primary source for current scientific news, webinars, virtual conferences, and more. LabRoots has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.

Share article on social media or email:

View article via:

Pdf Print

Contact Author

Karen Sorenson
LabRoots, Inc.
+1 (619) 861-0590
Email >
Visit website