D-Amino Acids: A Global Strategic Business Report
San Jose, CA (PRWEB) August 25, 2011
Global market for D-Amino acids is characterized by their increasing application in the pharmaceutical industry, biotechnology, immunodiagnostics, and food industry, as well as extensive research to unleash their potential in the discovery of novel drugs. D-Amino Acids also find use in biosensors, biomarkers, and biocatalysts, in addition to their application in the synthesis of biologically active peptide molecules, food additives, animal feed, biopesticides and antibiotics, among others. Further, an advantage conferred by D-Amino Acids over their L-counter parts is that D-Amino Acids are required in comparatively lower amounts in the aforementioned processes.
Nearly 70% of the pharmaceutical products are chiral molecules of various compounds, including Amino acids. Having become important chiral-building components for various pharmaceuticals and over 3 thousand amino acid derivatives, D-amino acids represent high-value intermediates in the pharmaceutical sector and find a number of applications in this area. The pharmaceutical intermediates industry is however dependant on the demand from players in the pharmaceutical sector.
Region-wise, Asia-Pacific represents the largest, as well as the fastest growing, market for D-Amino Acids, as stated by the new market research report on D-Amino Acids. The US, however, represents the single largest market for D-Amino Acids. Asia-Pacific is expected to be the fastest growing market globally, registering a compounded annual growth rate of 13% over the analysis period. Pharmaceuticals represent the largest end-use segment for D-amino acids, occupying a dominant share of the global market. Applications of D-Amino acids in other end-use segments, including research and development, is likely to record the highest compounded annual growth rate of more than 11% over the analysis period.
In the research and development arena, Korea-based AminoLogics Co. Ltd. has developed the ARCA or Alanine Racemase Chiral Analogue, a catalytic compound, which can be manufactured on a commercial scale in an economical way. The ARCA technology enables the inter-conversion of L- and D-Amino acids as well as the conversion of racemic mixtures of amino acids into L- or D-forms of amino acids. The breakthrough technology is expected to facilitate the manufacture of either L- or D- amino acids, and their derivatives in a comparatively economical way compared to the traditional methods.
Research on D-Amino Acids in food and feed additives, Pharmaceuticals, agrochemicals, and other industrial operations is increasing at a rapid pace. The market is witnessing the development of several new peptide molecules containing D-Amino Acids, as pharmaceutical and biotechnology companies recognize the therapeutic properties of peptide drugs. Presently, D-Amino Acids constitute the composition of various semi-synthetic antibiotics, such as Amoxicillin (D-4-hydroxyphenylglycine) and Ampicillin (D-phenylglycine) that possess a broad anti-microbial range. The drug Nafarelin that is indicated for the treatment of endometriosis contains D-2-Naphthylalanine. Additionally, D-Cycloserine and D-Penicillamine are reported to have antibacterial and anti-rheumatic properties, respectively. D-Amino Acids are emerging as valuable tools in the drug discovery efforts of the pharmaceutical industry.
The need to develop sensitive techniques for the detection of D-Amino Acids, initially driven by the need to detect their presence in food, has eventually made inroads into basic research in related areas. The wide-ranging functionality and structural diversity of D-Amino acids enables their use as molecular scaffolds as well as chiral building components for creating combinatorial libraries. Role of freely occurring D-Amino Acids in physiology and animal tissues is likely to emerge as a promising area of research, thereby enabling a better understanding of their biological function. In general, L-Amino acids are the naturally occurring amino acids, and hence D-Amino Acids cannot be synthesized in the same way as their L-counterparts. As such, enzymes associated with the synthesis of D-Amino Acids represent an area of growing interest among researchers, and the presence or absence of these enzymes across living forms would facilitate in establishing taxonomic relationships as well as in understanding biological evolution. These studies are expected to form the basis of novel techniques in biotechnology-based synthesis in the future.
Major players profiled in the report include AnaSpec Inc., EVONIK Industries AG, Genzyme Corporation, IRIS Biotech GmbH, Kyowa Hakko Kirin Co. Ltd., LifeSpan Biosciences Inc., Shanghai Hanhong Chemical Co. Ltd., Sekisui Medical Co. Ltd., Sichuan Tongsheng Amino acid Co. Ltd., Sigma-Aldrich Co., TCI America, Tocris Bioscience, Zhangjiagang Huachang Pharmaceutical Co. Ltd., among others.
The research report titled “D-Amino Acids: A Global Strategic Business Report” announced by Global Industry Analysts Inc., provides a comprehensive review of the D-Amino Acids market, their growing prominence, present applications and future potential, structural and functional aspects of D-amino acids, research and development activities including the research findings on select D-amino acids used in diet, innovations and developments in the D-amino acids space, the Alanine Racemase Chiral Analogue (ARCA) technology, recent industry activity, and profiles of major/niche global market participants. The report provides annual value sales estimates and projections for D-amino acids market for the years 2009 through 2017 for the following application areas – Pharmaceuticals, Industrial, and Others. Also, a six-year (2003-2008) historic analysis is provided for additional perspective.
For more details about this comprehensive market research report, please visit – http://www.strategyr.com/D_Amino_Acids_Market_Report.asp
About Global Industry Analysts, Inc.
Global Industry Analysts, Inc., (GIA) is a leading publisher of off-the-shelf market research. Founded in 1987, the company currently employs over 800 people worldwide. Annually, GIA publishes more than 1300 full-scale research reports and analyzes 40,000+ market and technology trends while monitoring more than 126,000 Companies worldwide. Serving over 9500 clients in 27 countries, GIA is recognized today, as one of the world's largest and reputed market research firms.
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