Yourwellness Magazine Takes a Closer Look at Ulcerative Colitis

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With a ulcerative colitis treatment receiving FDA priority review status, Yourwellness Magazine took a closer look at ulcerative colitis.

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An experimental treatment for adults with moderately to severely active ulcerative colitis has been granted priority review status by the US Food and Drug Administration (FDA), the Wall Street Journal reported September 4th. The article, “Takeda's Ulcerative Colitis Treatment Gets FDA Priority Review Status,” explained that Takeda Pharmaceutical Co.'s, Japan's biggest drug maker, submitted its biologics license application for vedolizumab in June, and the drug’s priority review status means that – if approved – vedolizumab would provide a significant improvement in safety or effectiveness and would require a shorter review period of eight months instead of a year. (

This inspired Yourwellness Magazine to take a closer look at the basics of ulcerative colitis. According to Yourwellness Magazine, “Ulcerative colitis is a long-term (chronic) condition affecting the colon. Symptoms include bloody diarrhoea, abdominal pain, a frequent need to go to the toilet and weight loss. These can range from mild to severe, with the condition being unpredictable. Symptoms can flare up and then disappear (known as remission) for months or even years.” Yourwellness Magazine explained that ulcerative colitis is thought to be an autoimmune condition, meaning the immune system mistakes harmless bacteria inside the colon as a threat and attacks the tissues of the colon, causing it to become inflamed. In severe cases, painful sores may form which bleed and produce mucus and pus. (

Yourwellness Magazine commented that as there is currently no cure for ulcerative colitis, the aim of treatment is to relieve symptoms during a flare-up and prevent symptoms from returning during remission – this is known as maintenance therapy. Yourwellness Magazine noted that while mild to moderate “flare-ups” can usually be treated at home, a severe flare-up needs treating in hospital as there is a chance of serious complications developing. Surgery may be required to remove a section of the colon, if medication fails to work.

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Michael Kitt
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