New Pilot Study Shows Active Ingredient in TFX Flex™ Joint Health Supplement Improves Joint Flexibility, Mobility and Comfort Leading to Joint Pain Relief

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A new pilot study published earlier this year in the Journal of Alternative and Complementary Medicine showed that UC-II®, the active ingredient found in the popular joint health supplement TFX Flex™ improves joint flexibility, mobility and comfort. The new study corroborates the results of an earlier human clinical study published in International Journal of Medical Science that showed the ingredient resulted in joint pain relief.

2X Better Than Glucosamine & Chondroitin

TFX Flex™ Joint Health Supplement

This product has been shown in clinical studies to be 2X more effective than glucosamine & chondroitin.

A company spokesman for TFX Health, LLC, announced earlier this week that, “A new pilot study published in the Journal of Alternative and Complementary Medicine has provided further clinical evidence that UC-II® Undenatured Type II Collagen promotes improved joint flexibility, mobility and comfort.” UC-II® is one of the key active ingredients found in the company’s popular TFX Flex™ joint health supplement.

The results of the new study published in 2013 corroborates the results of an earlier 2009 human clinical study published in the International Journal of Medical Science that showed that UC-II® was 2X more effective than glucosamine & chondroitin for joint pain relief [Int J Med Sci. 2009; 6:312-321].

The new 2013 randomized, double-blind, placebo controlled pilot study was conducted by JK Udani, MD of Medicus Research. The author of the study concluded that, “In a population of healthy subjects who only experience joint discomfort upon physical activity, UC-II® appears to be effective in alleviating joint discomfort.” The author further noted that, “Supplementation with UC-II® was well-tolerated and more effective than placebo in supporting joint comfort, flexibility, and mobility.” [JACM, 2013; 19:A4]

A TFX Health company spokesman explained, “The science behind joint health is rapidly changing. Glucosamine & chondroitin are no longer the only options for joint pain relief and certainly not the best option.”

Since its introduction more than 2 decades ago, the combination of glucosamine and chondroitin for joint support has dominated the joint health industry, exceeding $2 Billion in annual worldwide sales making it one of the best selling dietary supplements in history. Despite its dominance in the industry, glucosamine & chondroitin has recently come under fire from the scientific and medical community with serious questions about the efficacy of this combination for joint pain.

A study published in the British Medical Journal in 2010 concluded that, “glucosamine and chondroitin, either taken together or separately, have not shown a clinically significant improvement in joint pain relief for patients troubled with knee or hip osteoarthritis [BMJ 2010; 341:c4675].

More recently in 2012, the European Food Safety Authority (EFSA) denounced joint support claims for glucosamine. The EFSA panel concluded that, “a cause and effect relationship has not been established between the consumption of glucosamine and maintenance of normal joint cartilage in individuals with osteoarthritis” [EFSA Journal 2012;10(5):2691].

As part of its ongoing effort to offer better solutions for joint health, TFX Health, LLC teamed up with GNC earlier this year to launch TFX Flex™, a product formulated to offer a safe and effective solution for the entire musculoskeletal system. Since its introduction, TFX Flex™ has become GNC’s best selling triple threat for bone, muscle, and joint health.

TFX Flex™ was one of the first supplements on the market to contain UC-II®, the revolutionary dietary ingredient that has been proven in human clinical studies to be 2X more effective than Glucosamine & Chondroitin for joint pain relief. UC-II® was developed by a team of scientists with more than 25 years of experience in the development of patented, clinically proven dietary ingredients. It holds 7 international and U.S. patents and is supported by 9 human clinical studies, including research at Harvard Medical School.

The new research recently published in the Journal of Alternative and Complementary Medicine is yet another independent source supporting claims related to the safety and effectiveness of TFX Flex as a one of the best new joint health supplements available on the market.

To learn more about TFX Flex™ Joint Health Supplement please visit The product is also available at GNC.

About TFX Health, LLC

Based in Salt Lake City, TFX Health, LLC is an innovative pioneer in the development of advanced health and wellness products. Its brands include TFX Flex™ Joint Health Supplement, TFX Drive™ Testosterone Booster, TFX Elite™ Extreme Thermogenic, and other high end formulations. TFX Health products are manufactured in the USA in FDA registered, GMP compliant facilities and sold worldwide through online and traditional retail channels.

UC-II® is a trademark of InterHealth N.I. Clinical data available upon request. U.S. Patents 5,645,851; 5,637,321; 5,529,786; 5,750,144; 7,083,820; 7,846,487, EPO Patent 1435906B1 and worldwide patents pending.

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