US Perspective on Gluten-Related Diseases Published by Dove Medical Press

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There is still much to be learned about the development of gluten-related disorders and the apparent increase in incidence within the US.

Clinical and Experimental Gastroenterology has published the review “US perspective on gluten-related diseases”.

Going gluten free is not just a fad. For an increasing number of patients, the gluten free diet is a medical necessity. As corresponding author Dr. Vasagar says, “In this review of gluten-related disorders, we emphasize the word “disorder” because in most cases, one may return to a normal healthy life once the offending agent is removed or, in the case of wheat allergy, the allergy maybe outgrown. Wheat is a complicated grain containing multiple proteins, including gluten, which have the ability to provoke an immune response. To date, the protein or proteins responsible for non-celiac gluten sensitivity have not been established.”

Dr. Vasagar continues, “Gluten is a likely culprit however further work must be done. Certainly, our understanding of non-celiac gluten sensitivity will change as the mechanism behind the clinical presentation is uncovered. Although we have a better understanding of the pathophysiology of wheat allergy and celiac disease, focusing research efforts on the environmental factors that lead to loss of immune tolerance in these disorders will be important to ultimately understanding why allergic and autoimmune disorders are increasing.”

As Dr. Andreas Kaiser, Editor-in-Chief, explains, “Gluten-related disorders are on one hand a true entity, but on the other hand the food industry has developed its own marketing strategies on promoting gluten-free diets at a substantial cost to consumers. The authors provide an excellent overview on the objective pathophysiology of gluten-related disorders from a US perspective.”

Clinical and Experimental Gastroenterology is an international, peer reviewed, open access, online journal publishing original research, reports, editorials, reviews, and commentaries on all aspects of gastroenterology in the clinic and laboratory.

Dove Medical Press Ltd is a privately held company specializing in the publication of Open Access peer-reviewed journals across the broad spectrum of science, technology and especially medicine.

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Albert Chan
Dove Medical Press
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