Frailty Syndrome Overview Published by Dove Medical Press

Significant progress has recently been made in understanding the pathogenesis of frailty.

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(PRWEB) April 01, 2014

Clinical Interventions in Aging has published the review “Frailty syndrome: an overview”.

As corresponding author Dr Leng says, “Since the seminal paper on frailty phenotype published by Dr. Linda Fried and colleagues at Johns Hopkins in 2001, research both in the biological basis and clinical application of the frailty syndrome has taken off at an unprecedented speed. Partnering with colleagues in China, I attempt to provide a brief overview, to the best of our knowledge, about the current status of this internationally emphasized topic in geriatric medicine and aging research.”

Dr Leng continues, “Significant works are currently being developed across the globe, such as in Europe, Asia, and Americas. Inevitably, we may have missed some important work. We hope that this will serve as a starting point for further information exchange and knowledge dissemination as well as an enhancer for further research development of this important and exciting field.”

As Dr Walker, Editor-in-Chief, explains, “This paper discusses an issue of growing importance that is the focus of attention in gerontology and anti-aging therapies. Loss of muscle or sarcopenia and frailty progressively erode quality of life, independent living and eventually increase the risk for development of intrinsic diseases of aging. The authors have reviewed recent literatures of frailty syndrome and summarized its clinical applications and potential preventative and therapeutic interventions. My overall expression is that the paper is well written and has the potential to attract significant attention from health care practitioners focused upon aging and its consequences.”

Clinical Interventions in Aging is an international, peer-reviewed journal focusing on evidence-based reports on the value or lack thereof of treatments intended to prevent or delay the onset of maladaptive correlates of aging in human beings. Research topics include Alzheimer's disease, Dementia, Osteoporosis, and Geriatrics. The journal encourages concise rapid reporting of original research and reviews in aging. In addition, Clinical Interventions in Aging has a 5-year Impact Factor of 2.408.

Dove Medical Press Ltd is a privately held company specializing in the publication of Open Access peer-reviewed journals across the broad spectrum of science, technology and especially medicine.


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  • Angela Jones
    Dove Medical Press
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