Here at JayMac we are dedicated to educating the public and health care practitioners on MTHFR and homocysteine metabolism and how these relate to the treatment of autistic patients." Harold Robinson, CEO, JayMac Pharmaceuticals, LLC
Sunset, LA (PRWEB) April 07, 2014
What is MTHFR and why is it important in Autism? With Autism on the rise at a 30% increase, this is one of many questions needing answers. JayMac Pharmaceuticals has committed the month of April's media efforts to answering this question and more.
MTHFR (methylenetetrahydrofolate reductase) is responsible for converting folic acid to L-methylfolate. A common genetic mutation of MTHFR significantly decreases the body's ability to make this conversion, which results in high homocysteine, and this can cause many health problems, including decreased neurological functioning. Research is showing a major incidence of MTHFR in persons with autism.
According to Dr. Lawrence Ginsberg, MD, CEO of Red Oak Psychiatry, "In my clinical experience in testing my patients on the autism spectrum for MTHFR defects, 90% are heterozygous or homozygous for one of two alleles (C677T or A1298C) or are compound heterozygotes. This will dramatically decrease their ability to convert folic acid to L-methylfolate; this reduction can be as much as 70%."
Adequate supplementation is key to addressing the MTHFR defect. Supplementing the diet, or taking traditional nutritional supplements is not enough, because the genetic issues keep the body from using them. "Folic acid is not good enough, the components have to be methylated. L-Methylfolate is the engine. I have used EnLyte in autistic patients when there is a suspected or known methylfolate deficiency, in conjunction with other therapies," Dr. Ginsberg states.