New Research Finds Certain Types of Mesothelioma Patients More Likely to Benefit from Radical Surgery, According to Surviving Mesothelioma

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A team of Italian doctors say women, people with epithelial mesothelioma, and those who have chemotherapy before surgery will reap the most benefit from lung-removing surgery.

Factors Affecting Surgery Survival

Female patients, patients with epithelial tumors, and patients who received induction chemotherapy will best benefit from EPP.

A new study of more than 500 mesothelioma patients at nine Italian medical centers finds that certain characteristics can help define who is likely to benefit from the most radical type of surgery. The full story has just been posted on the Surviving Mesothelioma website and can be read by clicking here.

Thoracic surgeons with the European Institute of Oncology in Milan, the University of Padua, the National Cancer Institute in Rome and five other centers evaluated the surgical outcomes of mesothelioma patients based on their age, gender, cancer stage, histological subtype, and whether or not they had chemotherapy before or after surgery.

Reporting on their findings, lead author Dr. Lorenza Spaggiari of the European Institute of Oncology writes, “Female patients, patients with epithelial tumors, and patients who received induction chemotherapy will best benefit from EPP.”

The study, published in the Annals of Thoracic Surgery, found that the median overall survival for all study subjects was 18 months, but that more than a quarter of the mesothelioma patients were still alive 3 years after EPP surgery.

“This study is potentially good news for certain types of mesothelioma patients who are considering EPP,” observes Alex Strauss, Managing Editor for Surviving Mesothelioma. “The fact that it is a large study including patients from multiple centers gives even more credence to the findings.”

To learn more about the new study, including detailed surgery survival data, see Radical Surgery Outcomes Better in Women, available now on the Surviving Mesothelioma website.

Spaggiari, L et al, “Extrapleural Pneumonectomy for Malignant Mesothelioma: An Italian Multicenter Retrospective Study”, April 11, 2014, Annals of Thoracic Surgery, Epub ahead of print,

For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

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