AutismOne: The Cutting-Edge Autism Conference Presents Groundbreaking Advance: Discovery of Autism Nexus

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Conference keynote uncovers stunning progress in autism research, understanding, and direction

Jeff Bradstreet, MD

In a landmark study published this month in the Journal of Neuroinflammation, the research team of Professors Sinascalco and Bradstreet discovered a link between the endocannabinoid system and the vitamin D binding protein, GcMAF. Professor Bradstreet explained the laboratory experiments demonstrated the cannabinoid 2 receptor was abnormally regulated in the immune cells of children with autism and that the administration of GcMAF normalized the DNA regulation of the cannabinoid receptors. The authors state: "This study presents the first observations of GcMAF effects on the transcriptionomics of the endocannabinoid system and expression of CB2R protein. These data point to a potential nexus between endocannabinoids, vitamin D and its transporter proteins, and the immune dysregulations observed with autism." Bradstreet further states the implication of the cannabinoid dysregulation in autism helps explain the observations of gut-immune-brain linkage in autism since the CB2 receptors are expressed both on immune cells in the gut and microglial (immune) cells in the brain.

AutismOne Executive Director Teri Arranga described the May 24 keynote presentation at the AutismOne 2014 Conference, “The Autism Nexus: New Discoveries of Links Among the Gut Microbiome, the Immune System, and Brain Dysfunction and What YOU Can Do!” as follows: “Premier researchers Dr. James Jeffrey Bradstreet, Professor Marco Ruggiero of Italy, and Dr. Yi Jin of the Newport Brain Research Center will present cutting-edge innovations in autism therapies. Their research can explain the relationship of the immune system to brain function. Topics include vitamin D deficiency; vitamin D binding protein – GcMAF; magnetic resonant therapy, a unique application of transcranial magnetic brain stimulation; transcranial ultrasound, and the body’s endocannabinoid system. The preliminary findings of the controlled study on magnetic resonant therapy will be announced during the presentation.” She continued, “The new research is very important and exciting, and AutismOne is delighted to share this with the public.”

Information at the AutismOne 2014 Conference will cover all learning levels, serving those new to autism-related issues through those seeking more technical topics. Content areas include educational therapies, such as applied behavior analysis and Relationship Development Intervention®, culinary training, and more. The conference spans five days and offers over 100 speakers.

Said Arranga, “In addition to providing education toward restoration of health if an autism diagnosis has already occurred, AutismOne also seeks to educate and advocate for the prevention of autism and related disorders through common sense measures to support healthy neurodevelopment. We are proud to engage productively with like-minded organizations in pursuing this goal and are pleased to welcome community partners Focus Autism ( and the Children’s Medical Safety Research Institute ( to Chicago.”

To learn about how autism is preventable and treatable and to hear about how children can recover, visit the AutismOne 2014 Conference at the InterContinental Chicago O’Hare Hotel, May 21-25. Pre-registration is available at, or register on-site.

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Jody Grimaldi
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