Aid in Recovery Highlights the Impact of New Trace Amine-Associated Receptor 1 RO5263397 Drug in Reducing Cocaine Addiction

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Aid in Recovery released a statement today regarding a new report studying the effects of the Trace Amine-Associated Receptor (TAAR) 1 RO5263397 drug on cocaine addiction. According to the report, the RO5263397 drug type generated significant findings in the reduction of several cocaine addiction-related behavioral effects.

Aid in Recovery

Aid in Recovery

Cocaine and methamphetamines abuse is at an all-time high.

Aid in Recovery, a full service drug and alcohol treatment center servicing south Florida, released a statement today highlighting a new research report involving trace amine-associated receptor (TAAR) 1 RO5263397 as a key drug in reducing cocaine addiction.

The study report from Neuropharmacology (Effects of the trace amine-associated receptor 1 agonist RO5263397 on abuse-related effects of cocaine in rats, 5/14/2014), authored by researchers across the United States and China, suggested that TAAR 1 agonist RO5263397 is an effective drug target for the treatment of cocaine addiction.

The report investigated potential effects of TAAR 1 agonists on cocaine abuse-related behaviors. Through the use of behavioral economic analysis, the impact of RO5263397 was evaluated in more detail in relation to conditioned place preference (CPP), self-administration of cocaine, cue- and prime-induced reinstatement of cocaine-seeking behaviors, and cocaine-induced behavioral sensitization. While no change in cocaine consumption was observed, the report identified a significant correlation between the RO5263397 drug and the decrease of behaviors associated to cocaine demand.

While further research is necessary, the study’s findings provided the first comprehensive assessment of a specific TAAR 1 agonist’s impact on several cocaine-driven behaviors. The results emphasized the effective role of RO5263397 in treating a wide variety of drug abuse and addiction.

“Cocaine and methamphetamines abuse is at an all-time high,” said Dr. Michael Lukens, Psychologist at Aid in Recovery. “We are constantly on the search for new drug studies that can possibly reduce or even eliminate cravings associated with drug addiction and other related substance abuse. This new discovery about the RO5263397 drug type is exciting, because the drug could be extremely helpful in revolutionizing the way we approach treatments for various forms of substance abuse and drug addiction.”

Aid in Recovery is at the forefront of new research methods and techniques for effective substance abuse prevention as well as drug and alcohol addiction treatments. For more information on the services and treatments offered at Aid in Recovery, please visit

About Us

Aid in Recovery is a premier drug and alcohol treatment center. Our approach is defined by recognizing each clients need for a personalized drug and alcohol treatment program. We aren't a hospital-like institution and there’s a good reason for that. We believe that treating each client as an individual is crucial to delivering the best possible patient care. At a busy clinic-like program, it simply isn't possible for a therapist to truly get to know each client and understand their specific needs. To best meet the needs of each patient we treat, we offer a diverse curriculum with a focus on both mind and body designed to meet the individual. We treat every patient as an individual and we work with one patient at a time and guide them to a new life in recovery. To learn more about the specifics of our program, please visit our program details page.

View our drug and alcohol treatment services or give us a call: 1-855-223-6171.

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Dr. Michael Lukens
Aid in Recovery
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Edward Gabrielski
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