Frontier Pharma: Psoriasis - Identifying and Commercializing First-in-Class Innovation
Albany,New York (PRWEB) June 05, 2014
Researchmoz presents this most up-to-date research on "Frontier Pharma: Psoriasis - Identifying and Commercializing First-in-Class Innovation". The report focuses primarily on quantitative market metrics in order to characterize the growth and evolution of the market.
Psoriasis is a chronic, inflammatory disease triggered by deregulated Thymus-derived (T) cells, resulting inflammation and benign hyperplasia of keratinocytes within the skin. Manifestations of affected skin are red, thickened plaques with an overlying silver-white scale, which significantly impairs the patient’s physical and mental well-being. The primary cause of psoriasis is unknown, as are the mechanisms that lead to immune cells directing inflammatory responses towards the skin.
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Within the lucrative autoimmune market, the psoriasis market has grown considerably due to the repositioning of all three marketed Tumor Necrosis Factor (TNF) inhibitors: Humira (adalimumab) and Enbrel (etanercept) which were originally approved for rheumatoid arthritis, and also Remicade (infliximab), the first biologic to be approved for Crohn’s disease, an autoimmune disease which largely affects the gastrointestinal system.
Table of Contents
1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 The Case for Innovation
2.1 Growing Opportunities for Biologic Products
2.2 Diversification of Molecular Targets
2.3 Innovative First-in-Class Product Developments Remain Attractive
2.4 Changes in the Clinical and Commercial Environment Will be More Favorable to Products That Target Niche Indications and Patient Populations
2.5 Innovation in Psoriasis
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Adhesive bandage, also known as sticking plaster, is a wound care dressing product that is utilized as small dressing. Adhesive bandages are applied on the patients who have not undergone serious accident but have minor abrasion (scratches) and cut on their body. The most widely utilized term for adhesive bandage by Americans is Band-Aid or Bandage; however, the British population terms them as plaster. Adhesive bandage helps protect the cut or abrasion from bacteria, damage, friction and dirt and thus results in quick healing process of the wound. It also helps hold the skin’s two cut ends together and hence fasten the healing process. Adhesive bandage is covered with plastic, woven fabric or latex strip, which possesses the property of adhesion. A medicated absorbent pad with antiseptic solution is also present in an adhesive bandage. Some adhesive bandages contain thin and porous polymer coating on the medicated adsorbent pad that helps in sticking them to the wound.
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Delirium is a serious mental disorder which can cause two most common type of behaviors, namely hyperactive behavior, which is characterized by severe confusion, disorientation and disturbance in consciousness that fluctuates and hypoactive behavior, which is characterized by the sudden onset of withdrawal from interaction with the outside world. This serious mental disorder is mainly caused due to physical or mental illnesses, which is temporary and reversible in most of the cases. Major symptoms include clouding of consciousness, disorientation of thoughts, illusions, hallucinations, fluctuating levels of consciousness, dysphasia, dysarthria, tremors, asterixis in hepatic encephalopathy and uremia. Some major factors that cause delirium are withdrawal from alcohol or sedatives, drug abuse, chemical disturbances within the body, infections, strokes, dementia, poisoning and surgeries. Major driving factors for the growth of this market include increasing prevalence of various neurological disorders worldwide, rising number of cases of physical and mental illnesses, increasing prevalence of cardiovascular diseases and rising demand for advanced therapeutics.
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- An introduction to psoriasis, which includes symptoms, epidemiology, etiology, pathophysiology, diagnosis and treatment
- Analysis of the major systemic therapies in the current psoriasis marketed landscape
- Analysis of the pipeline for psoriasis, which includes a breakdown of pipeline molecules by phase of development, molecule type, molecular target and novelty. Psoriasis clinical trials are analyzed by size, duration and failure rates, and a comparative analysis of the most promising systemic pipeline molecules is also provided
- Forecast projections for the systemic psoriasis market to 2020. Analysis is provided for the global market and each of the eight major markets; the forecast incorporates projected, low and high variance scenarios based on treatment usage patterns and annual therapy costs in each of the major markets
- Analysis of strategic consolidations, including co-development and licensing deals, within the psoriasis indication
- Understand the current systemic psoriasis marketed products landscape and recognize the dominant therapeutic agents and pharmaceutical players involved.
- Observe projections for treatment usage patterns, annual therapy costs and market growth in the eight major markets and understand reasons for variance in projected patterns of growth in the eight major markets.
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