Yorba Linda, CA (PRWEB) September 04, 2014
Beckman Coulter is proud to support laboratories around the world, supplying innovative products to improve patient health and deliver trusted solutions for research and discovery. Along with LabRoots, Beckman Coulter announces a new learning webinar, titled “Physical & Chemical Characterization of Nanoparticle Constructs using the Analytical Ultracentrifuge.” The webinar will be broadcast live September 10th, 2014 at 7:00AM PT.
Colloidal nanoparticles have become important materials in biomedicine, catalysis, and optoelectronics. Their unique nanoscale properties stem from their size (particularly of the inorganic particle core) and surface composition of their organic ligand-shell. Given the polydispersity of nanoparticles, and complex composition, no technique other than Analytical Ultracentrifugation (AUC) has the potential to provide detailed information on the overall particle size, density, molecular weight and aggregation state in solution.
While AUC has become a standard tool for bioscientists to quantitatively study the size, confirmation, and interaction of macromolecules and proteins in solution for many decades, it has not had the same success with nanoparticles. Recent advancements in the mathematical modeling of the sedimentation boundaries have enabled the parameterization of the sedimentation and diffusion coefficients of all the species detected in solution during centrifugation in terms of their partial specific volume and molecular weight. This advancement opens the door to quantitative investigation of most nanoparticle systems by AUC - without a prior knowledge of their partial specific volume - since most nanoparticles have a constant shape which can be assessed by electron microscopy.
In this tutorial webinar Dr. Bakr will introduce some of the latest methods and procedures to analyze nanoparticles in solution with AUC. He will also provide insights on avoiding common experimental challenges that researchers face when studying nanoparticles with the AUC, which may lead to artifacts in the experimental data.
One of the industry’s prominent experts will present on September 10th:
LabRoots is the leading professional networking website designed to connect all science verticals. Founded in March 2008, LabRoot's vision was to connect the scientific world leveraging a myriad of unique features and tools, discovering meaningful collaborations across geographic boundaries and fields of expertise. LabRoots is the owner and producer of BioConference Live - which has grown into the world's largest series of virtual events within the Life Sciences and Clinical Diagnostics community.