New Study Finds Link Between Genes and Mesothelioma Location, Reports Surviving Mesothelioma

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Scientists say the chromosomes of asbestos-exposed people may influence what kind of mesothelioma they develop.

Mesothelioma and Chromosomal Abnormalities

Genes May Impact Mesothelioma Site

The pathway of the genetic abnormality might vary between pleural and peritoneal malignant mesothelioma.

Cancer researchers in Japan have identified chromosomal abnormalities that appear to have an impact on where mesothelioma develops in the body. Click here to read Surviving Mesothelioma’s new article on this important research.

Doctors with Nara Medical University report finding genetic differences between people with pleural mesothelioma (on the lung lining) and those with peritoneal mesothelioma (on the abdominal lining).

“Our study suggests that the pathway of the genetic abnormality might vary between pleural and peritoneal malignant mesothelioma,” writes lead investigator Dr. Maiko Takeda with the University’s Department of Diagnostic Pathology.

To conduct the study published in the Journal of Clinical Pathology, Dr. Takeda and his colleagues analyzed tissue samples from 54 mesothelioma patients.

“Understanding how genetics may impact mesothelioma development is an important step toward developing more effective gene-based treatments,” says Surviving Mesothelioma’s Managing Editor, Alex Strauss.

Full details of the study and its findings, including te exact chromosomal abnormalities associated with each type of mesothelioma, can be read in Study Finds Genes May Influence Site of Mesothelioma Tumors now available on the Surviving Mesothelioma website.

Takeda, M et al, “Comparison of genomic abnormality in malignant mesothelioma by the site of origin”, September 12, 2014, Journal of Clinical Pathology, Epub ahead of print,

For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

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Cancer Monthy
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