Antidepressant Drug Stops Herpes Symptoms; CBCD Reviews the Medical Evidence

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“Tranylcypromine, marketed since the 1960s as Parnate, inhibited initial herpes infection in animal tests,” according to a report published on on December 3, 2014. (1) The CBCD reviews the evidence and recommends two natural HSV remedies.

herpes remedy
Since there have been no human tests, and this drug is not FDA approved for use against herpes, the CBCD recommends using Novirin or Gene-Eden-VIR. - CBCD

“Infected with the herpes virus (HSV-1 or HSV-2)? The CBCD recommends taking Novirin or Gene-Eden-VIR.” - Greg Bennett, CBCD

The journal Science Translational Medicine published a study on December 3, 2014 which can be found at the following link ( ). The study found that the antidepressant drug, Tranylcypromine blocks the ability of the herpes virus to activate some of its own genes. “In blocking such viral gene activation, tranylcypromine makes an epigenetic change in the virus - an alteration in its gene activity that doesn’t change the underlying DNA structure. Since tranylcypromine targets a host protein and not the virus itself, it might reduce the evolution of drug-resistant viral strains, say the researchers, who are from the National Institute of Allergy and Infectious Diseases in Bethesda, Md., and other institutions.” (1) However, this drug has only been tested against the herpes virus in animals. “Tested in mice, rabbits and guinea pigs, tranylcypromine prevented some initial herpes infections and genital flare-ups … In guinea pigs, tranylcypromine reduced the amount of virus transmittable to other animals.” (1) The Center for the Biology of Chronic Disease (CBCD) believes that the results of the study mentioned above are encouraging. However, since there have been no human tests, and this drug is not FDA approved for use against herpes, the CBCD recommends using Novirin or Gene-Eden-VIR. These natural antiviral supplements have a formula that was shown to reduce herpes symptoms in two separate post-marketing clinical studies that followed FDA guidelines.

Click to learn more about herpes symptoms.

The formula of Novirin and Gene-Eden-VIR was tested by Hanan Polansky and Edan Itzkovitz from the CBCD. The studies showed that the Novirin and Gene-Eden-VIR formula is effective against the herpes simplex virus, and other viruses. The clinical studies were published in the peer reviewed, medical journal Pharmacology & Pharmacy, the first, in a special edition on Advances in Antiviral Drugs. Study authors wrote that, “individuals infected with the HSV … reported a safe decrease in their symptoms following treatment with Gene-Eden-VIR.” (2) The study authors also wrote that, “we observed a statistically significant decrease in the severity, duration, and frequency of symptoms.” (2)

Both products can be ordered online on the Novirin and Gene-Eden-VIR websites.

Novirin and Gene-Eden-VIR are natural antiviral dietary supplements. Their formula contains five natural ingredients: Selenium, Camellia Sinesis Extract, Quercetin, Cinnamomum Extract, and Licorice Extract. The first ingredient is a trace element, and the other four are plant extracts. Each ingredient and its dose was chosen through a scientific approach. Scientists at polyDNA, the company that invented and patented the formula, scanned thousands of scientific and medical papers published in various medical and scientific journals, and identified the safest and most effective natural ingredients against latent viruses. To date, Novirin and Gene-Eden-VIR are the only natural antiviral products on the market with published clinical studies that support their claims.

Until now, drugs approved for the treatment of HSV-2 infections include penciclovir, acyclovir, famciclovir, and valaciclovir. However, their effectiveness is limited. For instance, “a meta-analysis of five placebo-controlled and two dose comparison studies evaluated the effect of aciclovir, famciclovir or valaciclovir on symptoms. The meta-analysis showed that oral antiviral therapy decreases the duration and the associated pain of an outbreak by merely one day.” (2) There are also natural remedies that target the latent HSV. Two of these clinically backed remedies are Novirin and Gene-Eden-VIR.

The CDC notes that “Genital herpes is common in the United States. In the United States, about one out of every six people aged 14 to 49 years have genital herpes. You can get herpes by having vaginal, anal, or oral sex with someone who has the disease. Fluids found in a herpes sore carry the virus, and contact with those fluids can cause infection. You can also get herpes from an infected sex partner who does not have a visible sore or who may not know he or she is infected because the virus can be released through your skin and spread the infection to your sex partner(s).” (3)

“There are currently no FDA approved vaccines against the genital herpes virus.
In addition, research shows that most approved drugs against HSV-2 only reduce outbreaks by one day. Thus, we recommend that infected individuals take Novirin or Gene-Eden-VIR, which are designed to help the immune system target the latent HSV-2.” - Greg Bennett, CBCD

Click to learn more about Novirin and Genital Herpes, and Gene-Eden-VIR and Genital Herpes.


(1) Seppa, N. "Old drug reduces herpes symptoms, spread in animal tests.", December 3, 2014.

(2) Polansky, H. Itzkovitz, E. Gene-Eden-VIR Is Antiviral: Results of a Post Marketing Clinical Study. Published in September 2013.

(3) - Genital Herpes – CDC Fact Sheet. Last updated on July 1, 2014.

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