Synaptic Serotonin (5HT): Gut Work to Work Better in 2015 ~ New on the Bryan William Brickner Blog

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Working the serotonin dependent digestive system is the modulation focus in this Publius gut update. In three (brief) science tales based on new research from the National Institutes of Health (PubMed), one reads of new serotonin (5-HT, 5-hydroxytryptamine) research on colitis, glutamate and lactating Holsteins.

The Cannabis Papers by Publius (2011)

Stress on a lactating dairy cow hurts profits; life’s modulations, such as the stress of pregnancy, birth, and lactation, are serotonin system dependent – in all mammals, not just in Holstein dairy cows.

“Holstein dairy cows on serotonin,” chuckled Bryan W. Brickner, publisher of The Cannabis Papers, “and, of course, that’s for the high – and profit – of healthiness.”

In Synaptic Serotonin (5HT): Gut Work to Work Better in 2015 ~ New on the Bryan William Brickner Blog, serotonergic gut health is highlighted. The post focuses on new research from the National Institutes of Health (PubMed) to tell three (brief) serotonin gut tales regarding: serotonin transporters and colitis pathogenesis, serotonergic and glutamatergic dual signaling, and, one for our mammalian clade (a single branch of the tree of life), 5HT liver glucose homeostasis during transition from pregnancy to lactation (making milk) in Holstein dairy cows.

“Serotonin plays a genetic role in the pathogenesis of colitis,” explained Brickner, “and today’s science notes a significant association between colitis and a gene variant for the serotonin reuptake transporter (5-HTT).”

“We also find today that serotonergic raphe neurons co-release glutamate,” Brickner continued, “and that serotonin and glutamate components constitute a dual signal with distinct effects.”

“With the Holsteins it’s about stress,” closed Brickner; “stress on a lactating dairy cow hurts profits; life’s modulations, such as the stress of pregnancy, birth, and lactation, are serotonin system dependent – in all mammals, not just in Holstein dairy cows.”

Announcement: In January, look for Ew Publishing’s first booklet of 2015, Bryan W. Brickner’s Shivitti: A Review of Ka-Tzetnik 135633’s Vision. The heal Auschwitz nightmares via serotonin booklet will be available by (or before) 25 January 2015.

Brickner has a 1997 political science doctorate from Purdue University and is the author of several political theory books, to include Article the first of the Bill of Rights (2006) and The Book of the Is (2013); he also writes political fiction, such as the novella thereafter (2013). The Bryan William Brickner Blog is an ongoing resource for the political science of constitutions and the biological science of receptors.

Homeostasis next: Publius’ 2014 Cannabinoid Science Champions, Bivalency and Heteronomy, Wednesday 31 December 2014.

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Bryan W. Brickner
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