The rationale behind this protocol is to maximize both the tumoricidal and immunogenic potential of the radiotherapy...
Raleigh, NC (PRWEB) January 06, 2015
Scientists in Toronto say they have developed an effective method for pre-treating mesothelioma patients with radiotherapy prior to surgery. Click here to read the details of their report on induction therapy for mesothelioma on the Surviving Mesothelioma website.
Doctors at the Toronto Mesothelioma Research Program say they have used accelerated hemithoracic (one side of the chest) radiation followed by radical surgery to improve outcomes for patients with malignant pleural mesothelioma.
“The rationale behind this protocol is to maximize both the tumoricidal and immunogenic potential of the radiotherapy while minimizing the radiation toxicity to the ipsilateral [opposite side] lung,” reports Dr. Laura Donahoe, who wrote the report.
As part of the same report in Seminars in Thoracic and Cardiovascular Surgery, Dr. Donahoe and her colleagues also detail a number of other types of induction therapies currently being tested for mesothelioma.
“Most mesothelioma surgery patients will have to consider what type of first-line therapy is most likely to improve their odds of a good surgical outcome,” says Alex Strauss, Surviving Mesotheioma’s Managing Editor. “Because new induction therapies are constantly being tested, we think it is important for them to know what the latest options are.”
For more of the information in the Canadian report, including details of several ongoing mesothelioma clinical trials, see Induction Therapies Improve Mesothelioma Surgery Outcomes, now available on the Surviving Mesothelioma website.
Donahoe, L et al, “Novel induction therapies for pleural mesothelioma”, Autumn, 2014, Seminars in Thoracic and Cardiovascular Surgery, pp. 192-200, http://www.semthorcardiovascsurg.com/article/S1043-0679(14)00070-7/abstract
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