Beckman Coulter Webinar Series Presents Diversity of Extracellular Vesicles and Their Cargo in Cell-to-cell Communication

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The March 4, 2015 Webinar, hosted by LabRoots, will describe the background to extracellular vesicles and will discuss the diversity of extracellular vesicles released by single cell types in culture, and diversity of extracellular vesicles in body fluids, discussing their relevance for cell-to-cell communication.

Jan Olof Lötvall, MD, PhD - Professor, Department of Internal Medicine, University of Gothenburg

Beckman Coulter is sponsoring a new educational webinar, “Diversity of extracellular vesicles and their cargo in cell-to-cell communication,” which will focus on the study of extracellular vesicles and their relevance for cell-to-cell communication. The webinar is free to attend and will be broadcast live March 4, 2015 at 8:00am PT.

Every cell in the body can release several types of extracellular vesicles (EVs), often called “exosomes” or “microvesicles.” These vesicles carry a wide array of molecules, including functional proteins and enzymes, as well as different RNA species (mRNA, microRNA and other species), all protected by a membrane lipid bilayer. EVs have the capacity to deliver molecular cargo to recipient cells by multiple pathways, including fusion at the level of the cell membrane, or by being internalized by cells. Current research is suggesting a wide diversity of extracellular vesicles, with diverse morphology according to electron microscopy studies, and difference in RNA and protein cargo according to bioinformatics analyses.

Extracellular vesicles have been implicated in several ways in disease. For example, in cancer, it has been shown that the number of EVs increase in the circulation. EVs can propagate disease in several ways, for example in cancer by enhancing angiogenesis and propagating metastasis, as well inducing immune tolerance. Furthermore, several studies today have suggested that the cargo of EVs released in disease states such as cancer, including proteins and RNA, will fundamentally change, which can explain changes in function.

The speaker will be Jan Olof Lötvall, MD, PhD, Professor, Department of Internal Medicine, University of Gothenburg. Jan Lötvall is a Professor at the Department of Internal Medicine at University of Gothenburg since 2002, and led research in 2007 that showed exosomes can transfer functional RNA molecules between cells (Nature Cell Biology, >2300 citations). Having years of experience in translational lung research, Dr Lötvall’s current research also includes the biological function of exosomes and other extracellular vesicles, and their natural ability of transferring RNA between cells. Dr. Lötvall was instrumental in starting the International Society for Extracellular Vesicles (http://www.isev.org), he is the current President of the organization (2012-2016), which currently attracts >700 delegates to the annual meeting, which has a more than 20% annual growth.

The free webinar, hosted by LabRoots, will be presented on Wednesday, March 4, 2015 at 8:00am PDT, 11:00am EDT, 4:00pm GMT.

For full details and free registration, click here.

About Beckman Coulter:
Beckman Coulter develops, manufactures, and markets products that simplify, automate, and innovate complex biomedical testing. More than 275,000 Beckman Coulter systems operate in both diagnostics and life sciences laboratories on seven continents. For more than 75 years, the company’s products have been making a difference in peoples' lives by improving the productivity of medical professionals and scientists, supplying critical information for improving patient health, and delivering trusted solutions for research and discovery.

About LabRoots:
LabRoots is the leading scientific social networking website and producer of online educational events and webinars, as well as a powerful advocate in amplifying global networks and communities, and contributing to the advancement of science through content sharing capabilities and encouraging group interactions.

Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning. LabRoots has become a primary source for current scientific news, webinars, virtual conferences and more. Join for free and become part of the largest scientific learning community in the world.

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