New Study in Advances in Atrial Fibrillation-related Stroke Prevention Proceedings of a Symposium Presented at the European Stroke Conference, in Nice, France, 8 May 2014

Share Article

European Neurological Review (Touch Medical Media), a peer-reviewed, open access, bi-annual neurology journal, publish cutting-edge article by Pierre Amarenco, Werner Hacke, Bo Norrving, Natalia Rost.

News Image
In patients with atrial fibrillation (AF) the risk of stroke is substantially increased, especially in those who are elderly (over 75 years) or have risk factors such as previous stroke, heart failure or hypertension.

Atrial fibrillation (AF), the most common type of cardiac arrhythmia, substantially increases the risk and severity of stroke and has a highly negative effect on patient outcomes. AF is associated with a pro-thrombotic state and studies have shown it increases the risk of stroke fivefold. This increased risk is particularly great in the elderly aged ≥80 years in whom stroke occurrence is up to 45.8 %. AF is also associated with an increased severity of stroke and the proportion of patients with cardio-embolic stroke is markedly increased with a 30-day mortality of 25 %. Furthermore, the presence of AF with stroke almost doubles the death rate with a 1-year mortality of 50 %. Although these risks are well recognised, too few patients with AF receive preventative and adequate therapy to minimise their stroke risk. As a consequence, there is unnecessary morbidity and mortality. This article reports presentations and discussions from a satellite symposium to discuss the important and timely matter of stroke prevention in AF, which was convened at the 23rd European Stroke Conference held in Nice in May 2014.

Prevention of Atrial Fibrillation-related Stroke – Guidelines and Clinical Reality
Professor Werner Hacke (University of Heidelberg, Germany) considered the current recommendations for treating AF and how well these are being adhered to in Europe and elsewhere.

The Current Recommendations and Stroke Risk Classification
The European guidelines, established for over a decade, have identified the increased stroke risk in AF and set out strategies to minimise it. In the clinical classification scheme for predicting stroke (CHADS2) factors such as congestive heart failure, hypertension, age ≥75 years and diabetes each score 1 point and a previous stroke or transient ischaemic attack (TIA) scores 2 points. The sum of these points increases with stroke risk: total scores in the range 0 to 6 represent 1.9 to 18.2 strokes/100 patient years (without anticoagulant therapy).

To continue reading this peer-reviewed article in full for free please go to:

Note to Editors:
touchNEUROLOGY (a division of Touch Medical Media) provides independent, cutting-edge, peer-reviewed content from world renowned physicians, designed to lead the debate on health and to engage, inform, and support physicians in improving patient outcomes globally. provides an international platform for peer-reviewed content from industry-leading journals alongside other carefully selected sources and aims to support physicians, clinicians and leading industry professionals in continuously developing their knowledge, effectiveness and productivity within the field of neurology.

Our portfolio of peer-reviewed journals, European Neurological Review and US Neurology comprise of concise review articles which are designed to keep busy physicians up-to-date with the latest developments in their field and serve as a key reference resource for the international neurology community.

Share article on social media or email:

View article via:

Pdf Print

Contact Author

Barney Kent
Visit website