Nisso Announces Completion of NISSO HPC (Hydroxypropyl Cellulose) Production Capacity Expansion

Share Article

Nisso has completed production capacity expansion for NISSO HPC to respond to growth in worldwide demand. This supports growth of the the unique excipient NISSO HPC SSL-SFP, which can solve tablet manufacturing problems.


NISSO HPC (hydroxypropyl cellulose)

Production capacity of NISSO HPC has expanded, providing secure and responsive excipient supply to global nutraceutical and pharmaceutical customers.

Nippon Soda Co., Ltd. (Nisso) has completed capacity expansion and qualification on schedule, allowing the company to respond to the growth in worldwide demand for NISSO HPC. The expanded production facility in Nihongi, Japan now has multiple production lines that operate independently to provide increased supply security. A robust global warehouse and distribution network provides responsive supply to customers with short lead times. NISSO HPC is a highly efficient ingredient, often used as a tablet binder in pharmaceutical and nutraceutical products.

A particular focus of the expansion was to support growth in the unique, low-molecular weight, fine-powder excipient grade of hydroxypropyl cellulose, NISSO HPC SSL-SFP. “Many customers have found the SSL-SFP grade to provide superior problem solving performance in difficult tablet formulations. Usage levels as low as 1.0 to 1.5% have been shown to solve manufacturing problems like tablet capping or low hardness, allowing customers to increase tablet press speed,” commented Mr. Kenji Sugisawa, Global Manager of NISSO HPC.

Additionally, a harmonized standard for Hydroxypropyl Cellulose has been formally approved by the USP Monographs, European Pharmacopeia, and the Japanese Pharmacopeia on December 1, 2014. NISSO HPC produced after that date will conform to the harmonized standard and will make it easier for customers to develop a single product formulation that meets global regulatory requirements.

Nisso has a long history in the HPC market. 2017 will mark the 50th anniversary of the first HPC production; in 2020, the company will celebrate its 100th anniversary. The long-term vision called “Chemigress to 100” represents the Company’s ambition of “contributing to the sound development of society with the strength of chemistry.”

About Nippon Soda Co., Ltd.

Nippon Soda Co., Ltd. is a research-focused producer of advanced chemical-related technologies with applications including crop protection, pharmaceutical intermediates and excipients, food and feed additives, catalysts, dyestuffs, and specialty polymers. Based in Tokyo, Japan, Nippon Soda has a global network of subsidiaries and affiliates focused on bringing their unique chemical solutions to customers all over the world.

For more information, please visit:

Or contact:

Nisso America Inc.
88 Pine St, 14th Fl
New York NY 10005
Tel: +1-212-490-0350

Nisso Chemical Europe GmbH
Berliner Allee 42, 40212
Dusseldorf, Germany
Tel: +49-(0)-211-1306686-0

Nippon Soda Co., Ltd.
2-1 2-chome, Ohtemachi
Chiyoda-ku, Tokyo 100-8165 Japan
Tel: +81-3-3245-6159

Share article on social media or email:

View article via:

Pdf Print

Contact Author

Nisso HPC
Visit website