Study: Psoriasis Drug May Increase Shingles Risk; The Center for the Biology of Chronic Disease (CBCD) Reviews the Study

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“Treatment with both biologic medications and methotrexate was associated with a significant 66% increase in the incidence of herpes zoster,” according to a report on Family Practice News published on March 22, 2015. (1) The CBCD recommends Novirin against the latent herpes zoster virus.

herpes remedy
Reactivation of the shingles virus is associated with the use of certain drugs, such as methotrexate and certain biologic medications. (1)

“Infected with the varicella zoster virus (VZV), which causes shingles? The Center for the Biology of Chronic Disease (CBCD), which tested the formula of Novirin in two post-marketing clinical studies, recommends taking this natural antiviral supplement against the latent virus.” – Greg Bennett, CBCD

Herpes Zoster (HZ), commonly called shingles, is a distinctive syndrome caused by reactivation of varicella zoster virus (VZV), which also causes chickenpox. A study found that this reactivation is associated with the use of certain drugs, such as methotrexate and certain biologic medications. (1) “Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung. It is also used to treat severe psoriasis and rheumatoid arthritis.” (See from January 6, 2015) (2) Reactivation of VZV usually happens whenever immunity to VZV declines as a result of aging or immunosuppression (a damaged immune system). Medline Plus points out that “Methotrexate may decrease the activity of your immune system, and you may develop serious infections.” (See Medline Plus, from March 2, 2015) (3) Psoriasis itself is a “chronic inflammatory disorder of the immune system.” (See (4)

“The CBCD points out that many drugs, including Methotrexate, may damage the immune system. We urge the public to talk to their doctors about immune system damaging effects of any drugs they use.” - Greg Bennett, CBCD

Dr. Guy Shalom wrote that “our study results might suggest the need for … vaccination against VZV (varicella zoster virus).” (1) The CBCD points out that Zostavax is an existing vaccine that was found to reduce the risk of developing a shingles outbreak in 60% of those vaccinated. The vaccine also decreases the long-term pain from post-herpetic neuralgia (PHN). In adults vaccinated at age 60 years or older, however, protection from the vaccine decreases within the first 5 years after vaccination. (See the CDC, Last Reviewed on May 1, 2014) (5) The CBCD recommends that individuals who have ever had chickenpox take Novirin. The formula of this natural shingles remedy was designed to help the immune system target the latent form of the virus.

Click to learn more about Novirin.

The formula of Novirin tested by Hanan Polansky and Edan Itzkovitz from the CBCD in two clinical studies that followed FDA guidelines. The studies showed that the Novirin formula is effective against the herpes family of viruses. Varicella Zoster is a member of the herpes family. The clinical studies were published in the peer reviewed, medical journal Pharmacology & Pharmacy, the first, in a special edition on Advances in Antiviral Drugs. Study authors wrote that, “individuals infected with the (herpes viruses) … reported a safe decrease in their symptoms following treatment with Gene-Eden-VIR.” (6) The study authors also wrote that, “we observed a statistically significant decrease in the severity, duration, and frequency of symptoms.” (6)

Novirin can be ordered from the product website here:

Novirin is a natural antiviral dietary supplement. Its formula contains five natural ingredients: Selenium, Camellia Sinesis Extract, Quercetin, Cinnamomum Extract, and Licorice Extract. The first ingredient is a trace element, and the other four are plant extracts. Each ingredient and its dose was chosen through a scientific approach. Scientists at polyDNA, the company that invented and patented the formula, scanned thousands of scientific and medical papers published in various medical and scientific journals, and identified the safest and most effective natural ingredients against latent viruses.

To date, Novirin is the only natural antiviral product on the market with published clinical studies that support its claims.

The CDC notes that the varicella zoster virus (VZV), which is a herpes virus, causes both chickenpox and shingles. “After a person recovers from chickenpox, the virus stays dormant (inactive) in the body. For reasons that are not fully known, the virus can reactivate years later, causing shingles.” (5) Additionally, the CDC adds that “almost 1 out of every 3 people in the United States will develop shingles, also known as zoster or herpes zoster, in their lifetime. There are an estimated 1 million cases of shingles each year in this country. Anyone who has recovered from chickenpox may develop shingles; even children can get shingles. However the risk of shingles increases as you get older. About half of all cases occur in men and women 60 years old or older.” (5)

Are there treatments currently on the market, which target the Varicella Zoster Virus (VZV)?

Yes there are.

Antiviral drugs, such as Zovirax or Valtrex are designed to fight the shingles virus. However, these medications, when effective, only work to shorten the time of the shingles outbreak. They are ineffective against the latent VZV virus. (5)

In contrast, Novirin has an antiviral formula designed to target the latent VZV (shingles virus).

Click to learn more about Novirin and VZV.


(1) Family Practice News - Methotrexate and biologics linked to higher zoster risk in psoriasis. Published on March 22, 2015.

(2) - Methotrexate. Last revised on January 6, 2015.

(3) Medline Plus - Methotrexate. Last revised May 15, 2014.

(4) - Psoriasis and your immune system.

(5) - "Shingles (Herpes Zoster)" - Prevention & Treatment. Last Reviewed on May 1, 2014.

(6) Polansky, H. Itzkovitz, E. Gene-Eden-VIR Is Antiviral: Results of a Post Marketing Clinical Study. Published in September 2013.

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