NinePoint Medical Clinical Data at Digestive Disease Week® 2015

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New Clinical Data Using the NvisionVLE® Imaging System to be Presented at Digestive Disease Week® 2015

FOR IMMEDIATE RELEASE

Media Contact:
Patrick MacCarthy, NinePoint Medical, Inc.
(617) 475-2361 / pmaccarthy(at)ninepointmedical(dot)com

New Clinical Data Using the NvisionVLE® Imaging System to be Presented at Digestive Disease Week® 2015

Bedford, Mass. – May 15, 2015 – NinePoint Medical, Inc., an emerging leader in the development of medical devices for advanced imaging, today announced that new clinical data relating to its proprietary NvisionVLE® Imaging System, will be presented in a series of oral and poster presentations during Digestive Disease Week® (DDW®) 2015. The annual meeting will take place May 16-19th in Washington, DC.

The schedule for scientific presentations related to advanced optical coherence tomography (OCT) and the NvisionVLE® Imaging System at DDW 2015 is provided below.

SATURDAY, May 16, 2015

Three posters will be presented on Saturday, May 16 at 9:30am in Hall C of Walter E. Washington Convention Center.

Forum:     Barrett’s Esophagus: From Pathogenesis to Surveillance
Abstract Title:     Effacement of the Mucosal Layer observed with Volumetric Laser Endomicroscopy is not associated with Mucosal Density or Thickness of Barrett’s Esophagus
Presentation Number:    Sa1890

Forum:     Endoscopic Approaches to Pre-Malignant and Malignant Upper GI Disease Including Barrett’s Esophagus
Abstract Title:     Highly Selective Targeted Endoscopic Mucosal Resection for Early Esophageal Adenocarcinoma Using Combined Optical Endomicroscopic Modalities
Presentation Number:    Sa1088

Forum:     Imaging for the Esophagus
Abstract Title:     Potential Role of Volumetric Laser Endomicroscopy in Surveillance in Patients with Barrett’s Esophagus after Therapy
Presentation Number:    Sa1111

SUNDAY, May 17, 2015

Four oral presentations will be made the afternoon of Sunday, May 17 in Room 151A of the
Walter E. Washington Convention Center. These abstracts all address the topic of “Advanced Imaging Options in Barrett’s Esophagus”

Time:     2:00pm
Abstract Title:     Quantitative Analysis of Volumetric Laser Endomicroscopy (VLE) of Histologically Correlated Images Potentially Identifies Early Neoplasia in Barrett’s Esophagus
Presentation Number:    Su420

Time:     2:24pm
Abstract Title:     Computer-Assisted Image Interpretation of Volumetric Laser                             Endomicroscopy (VLE) in Barrett’s Esophagus
Presentation Number:    Su422

Time:     2:36pm
Abstract Title:     Can In-vivo Volumetric Laser Endomicroscopy (VLE) Detect Barrett’s Esophagus Dysplasia Missed on Surveillance Biopsies?
Presentation Number:    Su423

Time:     3:00pm
Abstract Title:     Neosquamous esophageal epithelium can be differentiated from Native esophageal squamous epithelium using volumetric laser endomicroscopy (VLE)
Presentation Number:    Su425

Four posters will be presented on Sunday, May 17 at 9:30am in Hall C of the Walter E. Washington Convention Center.

Forum:     New Technology: Diagnostic and Imaging
Abstract Title:     Atlas of high-quality histological correlations of Volumetric Laser Endomicroscopy (VLE) images of Barrett’s esophagus for identification of early neoplasia
Presentation Number:    Su1723

Forum:     New Technology: Diagnostic and Imaging
Abstract Title:     Ultrahigh Speed Endoscopic Optical Coherence Tomography        Angiography for Visualization of Subsurface Vasculature in Barrett’s Esophagus and Dysplasia
Presentation Number:    Su7175

Forum:     New Technology: Diagnostic and Imaging
Abstract Title:     Screening for Upper GI Disease in the Primary Care Office with Tethered Capsule OCT Endomicroscopy
Presentation Number:    Su1717

Forum:     Enhanced Endoscopic Imaging Including Molecular
Imaging; Spectroscopy and Fluorescence Imaging; and
Optical Coherence Tomography
Abstract Title:     Volumetric Laser Endomicroscopy (VLE) Demonstrates Clinical Benefit When Used During Surveillance Following Ablation of Barrett’s Esophagus
Presentation Number:    Su2033

MONDAY, May 18, 2015

Time:     9:30am
Forum:     Upper GI Small Bowel Imaging
Abstract Title:     Use of Optical Coherence Tomography (OCT) in the Evaluation of Gastric Lesions
Presentation Number:    Mo1551
Location:    Walter E. Washington Convention Center, Hall C

TUESDAY, May 19, 2015

Four posters will be presented on Tuesday, May 19 at 9:30am in Hall C of Walter E. Washington
Convention Center.

Forum:     Esophagus
Abstract Title:     Use of Optical Coherence Tomography (OCT) to Guide Endoscopic Mucosal Resection of Barrett’s Dysplasia
Presentation Number:    Tu1543

Forum:     Esophagus
Abstract Title:     Optical Coherence Tomography (OCT) Prior to Peroral Endoscopic Myotomy (POEM): A New Standard?
Presentation Number:    Tu1499

Forum:     Esophagus
Abstract Title:     Diagnostic Performance of In-vivo Volumetric Laser Endomicroscopy (VLE) for Detection of Barrett’s Esophagus Dysplasia
Presentation Number:    Tu1542

Forum:     Esophagus
Abstract Title:     Diagnostic Utility of Volumetric Laser Endo-microscopy (VLE) Surveillance in Patients with Barrett’s Esophagus in Routine Clinical Practice
Presentation Number:    Tu1545

For a demonstration of the NvisionVLE® Imaging System at DDW 2015, please visit the NinePoint Medical team in booth #2611.

The NvisionVLE® Imaging System is indicated for use as an imaging tool in the evaluation of human tissue microstructure, including esophageal tissue microstructure, by providing two-dimensional, cross-sectional, real-time depth visualization. The safety and effectiveness of this device for diagnostic analysis (i.e. differentiating normal versus specific abnormalities) in any tissue microstructure or specific disease has not been evaluated.

About Digestive Disease Week
Digestive Disease Week® (DDW®) is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. Jointly sponsored by the American Association for the Study of Liver Diseases (AASLD), the American Gastroenterological Association (AGA) Institute, the American Society for Gastrointestinal Endoscopy (ASGE) and the Society for Surgery of the Alimentary Tract (SSAT). More information can be found at http://www.ddw.org.

About The NvisionVLE™ Imaging System
NinePoint Medical’s proprietary NvisionVLE® Imaging System enables physicians and pathologists to endoscopically view cross-sectional images of the esophagus with 7 micron resolution and up to 3mm deep, in real-time. This advanced form of optical coherence tomography (OCT), also known as VLE (volumetric laser endomicroscopy), can be used to aid clinical decision-making relative to biopsy placement or treatment planning.

NinePoint Medical licensed this advanced OCT technology in 2010 from Massachusetts General Hospital (MGH), where it was developed at the Wellman Center for Photomedicine.

The FDA-cleared NvisionVLE® Imaging System is indicated for use as an imaging tool in the evaluation of human tissue microstructure, including esophageal tissue microstructure, by providing two-dimensional, cross-sectional, real-time depth visualization. The safety and effectiveness of this device for diagnostic analysis (i.e. differentiating normal versus specific abnormalities) in any tissue microstructure or specific disease has not been evaluated.

About NinePoint Medical, Inc.
NinePoint Medical, Inc. is a privately-held, commercial-stage medical device company developing innovative and cost-effective solutions for in vivo imaging. The proprietary NvisionVLE® Imaging System enables physicians and pathologists, for the first time, to view real-time, high-resolution, volumetric images of esophageal tissue up to 3mm below the surface. Headquartered in Boston, Massachusetts, NinePoint is backed by Third Rock Ventures, Prospect Venture Partners and Corning Inc. For more information, please visit http://www.ninepointmedical.com.

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